Influence of hay and animal feed exposure on respiratory status: a longitudinal study

被引：30

作者：

Thaon, I. ^{[1
,3
]}

Thiebaut, A. ^{[1
]}

Jochault, L. ^{[2
]}

Lefebvre, A. ^{[2
]}

Laplante, J. J. ^{[4
]}

Dalphin, J. C. ^{[2
,3
]}

机构：

[1] Univ Hosp Besancon, Occupat Dis Dept, Besancon, France

[2] Univ Hosp Besancon, Chest Dis Dept, Besancon, France

[3] Univ Franche Comte, CNRS, UMR 6249, Lab Chronoenvironm, F-25030 Besancon, France

[4] Mutual Sociale Agr Besancon, Besancon, France

来源：

EUROPEAN RESPIRATORY JOURNAL | 2011年 / 37卷 / 04期

关键词：

Asthma; chronic bronchitis; farming; longitudinal studies; respiratory function tests; ART; NO; E3; DAIRY FARMERS; LUNG-FUNCTION; CHRONIC-BRONCHITIS; AGRICULTURAL PRACTICES; DOUBS PROVINCE; SYMPTOMS; WORKERS; HEALTH; PREVALENCE;

D O I：

10.1183/09031936.00122209

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Our aim was to study respiratory symptoms and lung function decline in farmers, with particular attention to the influence of handling hay, straw and animal feed. From a cohort recruited in 1993-1994, 219 (82.6%) dairy farmers, 130 (62.5%) nondairy agricultural workers and 99 (66.4%) controls were re-evaluated in 2006. They answered medical and occupational questionnaires, underwent spirometric tests at both evaluations and pulse oximetry in 2006. Dairy and nondairy agricultural workers showed an increased risk for usual morning phlegm (adjusted OR 4.27 (95% CI 1.41-12.95) and 3.59 (95% CI 1.16-11.10), respectively). Animal feed handling was associated with increased risks of wheezing (p=0.01) and usual morning phlegm (p=0.04); hay or straw handling was associated with increased risk of wheezing (p=0.008). Adjusting for smoking, age, height, sex and altitude, dairy farmers had greater declines in forced expiratory volume in 1 s (FEV1)/forced vital capacity ratio (p=0.01) than controls. An increased decline in FEV1 for all agricultural workers was associated with animal feed handling, both measured as a categorical (currently versus never handling; p=0.05) or quantitative value (years of exposure during the survey period; p=0.03). Hay, straw or animal feed handling represents a risk factor of bronchial symptoms and, for animal feed only, of accelerated decline in expiratory flows.

引用

页码：767 / 774

页数：8

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