The Debate is Over: Continue Anti-Tumor Necrosis Factor Therapy Throughout Pregnancy

被引：8
作者：
Mao, Eric J. [1 ]
Mahadevan, Uma [2 ]
机构：
[1] Univ Calif Davis, Davis, CA 95616 USA
[2] Univ Calif San Francisco, San Francisco, CA 94143 USA
来源：
AMERICAN JOURNAL OF GASTROENTEROLOGY | 2018年 / 113卷 / 11期
关键词：
INFLAMMATORY-BOWEL-DISEASE; CROHNS-DISEASE; RISK-FACTOR;
D O I：
10.1038/s41395-018-0254-x
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Data in support of the safety of biologic use during pregnancy continues to grow. Utilizing a national French database with linkage between mothers and children, Luu et al. demonstrated that anti-tumor necrosis factor (anti-TNF) therapy exposure did not increase infection risk in children, though the mothers had higher rates of infection. Stopping therapy prior to 24 weeks gestation led to a higher rate of disease flares in the mother with no benefit to the infant compared to continued therapy.
引用
收藏
页码：1590 / 1591
页数：2
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