Direct intracystic biopsy and pancreatic cystoscopy through a 19-gauge needle EUS

被引:42
作者
Aparicio, Jose R. [1 ]
Martinez, Juan [1 ]
Niveiro, Maria [2 ]
Cabezas, Antonio [2 ]
Ruiz, Francisco [1 ]
De Madaria, Enrique [3 ]
Casellas, Juan A. [1 ]
机构
[1] Hosp Gen Univ Alicante, Endoscopy Unit, Alicante 03013, Spain
[2] Hosp Gen Univ Alicante, Dept Pathol, Alicante 03013, Spain
[3] Hosp Gen Univ Alicante, Gastroenterol Sect, Alicante 03013, Spain
关键词
CYSTIC LESIONS; DIAGNOSIS; ASPIRATION; PREVALENCE;
D O I
10.1016/j.gie.2010.08.036
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background: Histologic diagnosis of cystic pancreatic lesions (CPLs) is often difficult because of the low sensitivity of FNA and brush cytology. Objective: To discover whether obtaining biopsy samples from the cystic wall could increase the diagnostic yield of these lesions. Design: A pilot study including 2 patients with CPLs. Setting: Endoscopy unit in a tertiary-care hospital. Patients: Two women with CPLs located at the pancreatic head. Interventions: On EUS, biopsy forceps and a Spy Glass fiberoptic were passed through a 19-gauge needle to visualize and obtain samples from the cystic wall. Main Outcome Measurements: The histologic assessment was based on the obtained biopsy samples. Results: Both CPLs were considered to be mucinous cystoadenomas, because mucinous-like cylindric epithelium without cellular atypia was observed. Limitations: Pilot study. Conclusions: Obtaining biopsy samples from the wall of a CPL is now feasible. It represents a significant advantage in the diagnostic yield of this type of lesion.
引用
收藏
页码:1285 / 1288
页数:4
相关论文
共 10 条
[1]  
Ahmad NA, 2001, AM J GASTROENTEROL, V96, P3295
[2]   Safety and efficacy of cytology brushings versus standard fine-needle aspiration in evaluating cystic pancreatic lesions: a controlled study [J].
Al-Haddad, M. ;
Gill, K. R. S. ;
Raimondo, M. ;
Woodward, T. A. ;
Krishna, M. ;
Crook, J. E. ;
Skarvinko, L. N. ;
Jamil, L. H. ;
Hasan, M. ;
Wallace, M. B. .
ENDOSCOPY, 2010, 42 (02) :127-132
[3]   Diagnosis of pancreatic cystic neoplasms: A report of the cooperative pancreatic cyst study [J].
Brugge, WR ;
Lewandrowski, K ;
Lee-Lewandrowski, E ;
Centeno, BA ;
Szydlo, T ;
Regan, S ;
del Castillo, CF ;
Warshaw, AL .
GASTROENTEROLOGY, 2004, 126 (05) :1330-1336
[4]   Performance of endo sonography-guided fine needle aspiration and biopsy in the diagnosis of pancreatic cystic lesions [J].
Frossard, JL ;
Amouyal, P ;
Amouyal, G ;
Palazzo, L ;
Amaris, J ;
Soldan, M ;
Giostra, E ;
Spahr, L ;
Hadengue, A ;
Fabre, M .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2003, 98 (07) :1516-1524
[5]   Prevalence of unsuspected pancreatic cysts on MDCT [J].
Laffan, Thomas A. ;
Horton, Karen M. ;
Klein, Alison P. ;
Berlanstein, Bruce ;
Siegelman, Stanley S. ;
Kawamoto, Satomi ;
Johnson, Pamela T. ;
Fishman, Elliot K. ;
Hruban, Ralph H. .
AMERICAN JOURNAL OF ROENTGENOLOGY, 2008, 191 (03) :802-807
[6]   Pancreatic Incidentalomas: High Rate of Potentially Malignant Tumors [J].
Lahat, Guy ;
Ben Haim, Mendy ;
Nachmany, Ido ;
Sever, Ronen ;
Blachar, Arye ;
Nakache, Richard ;
Klausner, Josef M. .
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 2009, 209 (03) :313-319
[7]   Prevalence of Incidental Pancreatic Cysts in the Adult Population on MR Imaging [J].
Lee, Karen S. ;
Sekhar, Aarti ;
Rofsky, Neil M. ;
Pedrosa, Ivan .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2010, 105 (09) :2079-2084
[8]   Utility of EUS in the evaluation of cystic pancreatic lesions [J].
Sedlack, R ;
Affi, A ;
Vazquez-Sequeiros, E ;
Norton, ID ;
Clain, JE ;
Wiersema, MJ .
GASTROINTESTINAL ENDOSCOPY, 2002, 56 (04) :543-547
[9]  
Thomas T, 2010, J PANCREAS, V11, P163
[10]   Cyst fluid analysis in the differential diagnosis of pancreatic cystic lesions: a pooled analysis [J].
van der Waaij, LA ;
van Dullemen, HM ;
Porte, RJ .
GASTROINTESTINAL ENDOSCOPY, 2005, 62 (03) :383-389