Sorting It Out in Endosomes: An Emerging Concept in Renal Epithelial Cell Transport Regulation

被引：23

作者：

Welling, Paul A. ^{[1
]}

Weisz, Ora A. ^{[2
,3
]}

机构：

[1] Univ Maryland, Sch Med, Dept Physiol, Baltimore, MD 21201 USA

[2] Univ Pittsburgh, Dept Med, Pittsburgh, PA USA

[3] Univ Pittsburgh, Dept Cell Biol & Physiol, Renal Electrolyte Div, Pittsburgh, PA USA

来源：

PHYSIOLOGY | 2010年 / 25卷 / 05期

关键词：

CLATHRIN-MEDIATED ENDOCYTOSIS; EPIDERMAL-GROWTH-FACTOR; TRANSMEMBRANE CONDUCTANCE REGULATOR; COATED-PIT DYNAMICS; PROTEIN-KINASE-C; MDCK CELLS; PROXIMAL TUBULE; SODIUM-CHANNEL; RECYCLING ENDOSOMES; PLASMA-MEMBRANE;

D O I：

10.1152/physiol.00022.2010

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Ion and water transport by the kidney is continually adjusted in response to physiological cues. Selective endocytosis and endosomal trafficking of ion transporters are increasingly appreciated as mechanisms to acutely modulate renal function. Here, we discuss emerging paradigms in this new area of investigation.

引用

页码：280 / 292

页数：13

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