PET/CT and PET/MRI in ophthalmic oncology (Review)

被引：21

作者：

Kalemaki, Maria S. ^{[1
]}

Karantanas, Apostolos H. ^{[2
,3
]}

Exarchos, Dimitris ^{[4
]}

Detorakis, Efstathios T. ^{[5
]}

Zoras, Odysseas ^{[6
]}

Marias, Kostas ^{[3
]}

Millo, Corina ^{[7
]}

Bagci, Ulas ^{[8
]}

Pallikaris, Ioannis ^{[5
]}

Stratis, Andreas ^{[3
]}

Karatzanis, Ioannis ^{[3
,5
]}

Perisinakis, Kostas ^{[9
]}

Koutentakis, Pavlos ^{[1
]}

Kontadakis, Georgios A. ^{[5
]}

Spandidos, Demetrios A. ^{[10
]}

Tsatsakis, Aristidis ^{[11
]}

Papadakis, Georgios Z. ^{[2
,3
]}

机构：

[1] Venizeleio Gen Hosp Herakl, Dept Ophthalmol, Iraklion 71409, Greece

[2] Univ Crete, Sch Med, Dept Radiol, Iraklion 71003, Greece

[3] Fdn Res & Technol Hellas FORTH, Computat Biomed Lab CBML, N Plastira 100, Iraklion 70013, Greece

[4] Evangelismos Med Ctr, Dept CT MRI & PET CT, Athens 10676, Greece

[5] Univ Crete, Sch Med, Dept Ophthalmol, Iraklion 71003, Greece

[6] Univ Crete, Sch Med, Dept Surg Oncol, Iraklion 71003, Greece

[7] NIH, Positron Emiss Tomog Dept, CC, Bethesda, MD 20814 USA

[8] UCF, CRCV, Orlando, FL 32816 USA

[9] Univ Crete, Sch Med, Dept Med Phys, Iraklion 71003, Greece

[10] Univ Crete, Sch Med, Lab Clin Virol, Iraklion 71003, Greece

[11] Univ Crete, Sch Med, Lab Forens Sci & Toxicol, Iraklion 71003, Greece

来源：

INTERNATIONAL JOURNAL OF ONCOLOGY | 2020年 / 56卷 / 02期

关键词：

orbital tumors; ocular tumors; positron emission tomography; computed tomography; magnetic resonance imaging; cancer; staging; EMISSION TOMOGRAPHY/COMPUTED TOMOGRAPHY; SQUAMOUS-CELL CARCINOMA; GA-68-DOTATATE-AVID TUMOR VOLUME; DYSPLASIA MIMICKING MALIGNANCY; POLYOSTOTIC FIBROUS DYSPLASIA; INTENSELY INCREASED ACTIVITY; INCREASED METABOLIC-ACTIVITY; OPTIC PATHWAY GLIOMA; UVEAL MELANOMA; 18F-FDG PET/CT;

D O I：

10.3892/ijo.2020.4955

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Orbital and ocular anatomy is quite complex, consisting of several tissues, which can give rise to both benign and malignant tumors, while several primary neoplasms can metastasize to the orbital and ocular space. Early detection, accurate staging and re-staging, efficient monitoring of treatment response, non-invasive differentiation between benign and malignant lesions, and accurate planning of external radiation treatment, are of utmost importance for the optimal and individualized management of ophthalmic oncology patients. Addressing these challenges requires the employment of several diagnostic imaging techniques, such as high-definition digital fundus photography, ultrasound imaging, optical coherence tomography, optical coherence tomography (OCT)-angiography, computed tomography (CT) and magnetic resonance imaging (MRI). In recent years, technological advances have enabled the development of hybrid positron emission tomography (PET)/CT and PET/MRI systems, setting new standards in cancer diagnosis and treatment. The capability of simultaneously targeting several cancer-related biochemical procedures using positron emitting-radiopharmaceuticals, while morphologically characterizing lesions by CT or MRI, together with the intrinsic quantitative capabilities of PET-imaging, provide incremental diagnostic information, enabling accurate, highly efficient and personalized treatment strategies. Aim of the current review is to discuss the current applications of hybrid PET/CT and PET/MRI imaging in the management of patients presenting with the most commonly encountered orbital and ocular tumors.

引用

页码：417 / 429

页数：13