Characteristics and Outcomes of Children With Cystic Fibrosis Hospitalized With Cirrhosis in the United States

被引：4

作者：

Thornton, Christina ^{[1
]}

Somayaji, Ranjani ^{[1
,2
,3
]}

Parkins, Michael ^{[1
,2
]}

Swain, Mark G. ^{[1
]}

Ramos, Kathleen J. ^{[4
]}

Goss, Christopher H. ^{[4
]}

Shaheen, Abdel A. ^{[1
,2
,3
]}

机构：

[1] Univ Calgary, Cumming Sch Med, Dept Med, Calgary, AB, Canada

[2] Univ Calgary, Dept Microbiol Immunol & Infect Dis, Calgary, AB, Canada

[3] Univ Calgary, Dept Community Hlth Sci, Calgary, AB, Canada

[4] Univ Washington, Dept Med, Seattle, WA 98195 USA

来源：

AMERICAN JOURNAL OF GASTROENTEROLOGY | 2021年 / 116卷 / 08期

关键词：

LIVER-DISEASE;

D O I：

10.14309/ajg.0000000000001275

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

INTRODUCTION: To describe the characteristics and outcomes of children with cystic fibrosis (CF) hospitalized with cirrhosis in the United States. METHODS: We conducted a population-based cohort study of hospitalizations among children with CF using the 2016 Kid's Inpatient Database. RESULTS: In total, 9,615 admissions were analyzed. Diagnosis of cirrhosis was present in 509 (5.3%) and was significantly associated with increased mortality, length of stay, and hospital charges compared with those without cirrhosis. Hepatic encephalopathy was significantly associated with death in children with cirrhosis. DISCUSSION: Future interventions should be designed to support children with CF who have cirrhosis to improve clinical outcomes.

引用

页码：1734 / 1737

页数：4

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