Adult Atypical Teratoid/Rhabdoid Tumor in the Pineal Region: Case Report and Literature Review

被引:7
作者
Monteiro, Joana [1 ]
Santiago, Bruno [1 ]
Manilha, Rui [1 ]
Viegas, Catarina [1 ]
Oliveira, Ana [2 ]
Cunha e Sa, Manuel [1 ]
机构
[1] Hosp Garcia de Orta, Dept Neurosurg, Almada, Portugal
[2] Hosp Garcia de Orta, Dept Pathol, Almada, Portugal
关键词
Adult; Pineal region; Teratoid rhabdoid tumor; CENTRAL-NERVOUS-SYSTEM; TERATOID RHABDOID TUMOR; MULTIMODAL THERAPY; AT/RT; INFANCY;
D O I
10.1016/j.wneu.2019.11.075
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
BACKGROUND: Atypical teratoid/rhabdoid tumor (AT/RT) is a malignant embryonal central nervous system tumor with a poor prognosis. Its occurrence in the pineal region is extremely rare, with only 6 cases in adults reported so far. CASE DESCRIPTION: We report on a puerperal woman with an AT/RT in the pineal region. Total tumor resection was performed. Definitive diagnosis was confirmed by the loss of nuclear INI1/SMARCB1 staining. The patient underwent radiotherapy and chemotherapy with no evidence of recurrence at 31 months after surgery. CONCLUSIONS: This case highlights the importance of immunohistochemistry in the diagnosis of the disease and the importance of an aggressive treatment.
引用
收藏
页码:428 / 433
页数:6
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