Adult Atypical Teratoid/Rhabdoid Tumor in the Pineal Region: Case Report and Literature Review

被引：7

作者：

Monteiro, Joana ^{[1
]}

Santiago, Bruno ^{[1
]}

Manilha, Rui ^{[1
]}

Viegas, Catarina ^{[1
]}

Oliveira, Ana ^{[2
]}

Cunha e Sa, Manuel ^{[1
]}

机构：

[1] Hosp Garcia de Orta, Dept Neurosurg, Almada, Portugal

[2] Hosp Garcia de Orta, Dept Pathol, Almada, Portugal

来源：

WORLD NEUROSURGERY | 2020年 / 134卷

关键词：

Adult; Pineal region; Teratoid rhabdoid tumor; CENTRAL-NERVOUS-SYSTEM; TERATOID RHABDOID TUMOR; MULTIMODAL THERAPY; AT/RT; INFANCY;

D O I：

10.1016/j.wneu.2019.11.075

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

BACKGROUND: Atypical teratoid/rhabdoid tumor (AT/RT) is a malignant embryonal central nervous system tumor with a poor prognosis. Its occurrence in the pineal region is extremely rare, with only 6 cases in adults reported so far. CASE DESCRIPTION: We report on a puerperal woman with an AT/RT in the pineal region. Total tumor resection was performed. Definitive diagnosis was confirmed by the loss of nuclear INI1/SMARCB1 staining. The patient underwent radiotherapy and chemotherapy with no evidence of recurrence at 31 months after surgery. CONCLUSIONS: This case highlights the importance of immunohistochemistry in the diagnosis of the disease and the importance of an aggressive treatment.

引用

页码：428 / 433

页数：6

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