Increased carbohydrate antigen 19-9 expression in a thymic neuroendocrine tumor

被引：0

作者：

Shimizu, Yuki ^{[1
,2
]}

Kanda, Shintaro ^{[1
]}

Fukushima, Toshirou ^{[1
]}

Kobayashi, Takashi ^{[1
]}

Kondo, Ryoichi ^{[3
]}

Koizumi, Tomonobu ^{[1
]}

机构：

[1] Shinshu Univ, Sch Med, Div Gastroenterol, Dept Hematol & Med Oncol, Matsumoto, Nagano, Japan

[2] Shinshu Univ, Dept Internal Med, Div Gastroenterol, Sch Med, Matsumoto, Nagano, Japan

[3] Natl Hosp Org Matsumoto Med Ctr, Dept Thorac Surg, Matsumoto, Nagano, Japan

来源：

THORACIC CANCER | 2021年 / 12卷 / 21期

关键词：

immunohistochemical stain; neuroendocrine tumor; thymic carcinoid; tumor marker; MEDULLARY-THYROID CANCER; BONE METASTASES; CA-19-9; MARKER;

D O I：

10.1111/1759-7714.14153

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Here, we report a case of carbohydrate antigen (CA) 19-9-producing mediastinal neuroendocrine tumor (NET) (atypical carcinoid). A 54-year-old woman with no specific relevant medical history was referred to our hospital because of increased CA19-9 (95.3 U/ml) detected on health screening. Chest computed tomography (CT) revealed an anterior mediastinal mass without localized lymphadenopathy. Thoracic surgery was performed and the histopathological diagnosis was thymic CA19-9-positive NET. The patient developed mediastinal lymph node metastasis at 1 year (CA19-9: 413 U/ml) and multiple bone metastases 4 years (CA19-9: 2303 U/ml) after surgery. Increased CA19-9 levels paralleled the clinical courses of relapse. To our knowledge, this is the first report of CA19-9-producing thymic NET.

引用

页码：2949 / 2952

页数：4

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