Comparison of feasibility between hypodermoclysis and intravenous hydration among palliative care patients in Thailand

Background: Hypodermoclysis is a method of subcutaneous fluid administration. It has been used to treat palliative patients safely and effectively. However, the use of subcutaneous hydration is often overlooked. Aim: This study aimed to compare the feasibility, pain experience and acceptability between subcutaneous and intravenous hydration in a hospital setting. Methods: A prospective, randomised clinical trial was conducted. Patients requiring fluid administration were randomly allocated an intravenous or subcutaneous route. Patients' pain score, satisfaction and acceptance levels were collected.The difficulty score of the needle insertion and acceptance scores from nurses were recorded. Findings: A total of 26 patients were enrolled. The difficulty scores and patients' pain scores were significantly lower in the subcutaneous group. The satisfaction and acceptance levels of the patients and nurses were similar in both groups. No systemic side-effects were found in either group. Conclusion: Hypodermoclysis was acceptable and satisfying to patients and nurses. It was less painful than the intravenous route.