A paper-based chemiluminescence device for the determination of ofloxacin

被引：40

作者：

Liu, Wei ^{[1
]}

Guo, Yumei ^{[1
]}

Li, Huifang ^{[1
]}

Zhao, Mei ^{[1
]}

Lai, Zesheng ^{[1
]}

Li, Baoxin ^{[1
]}

机构：

[1] Shaanxi Normal Univ, Key Lab Analyt Chem Life Sci Shaanxi Prov, Sch Chem & Chem Engn, Xian 710062, Peoples R China

来源：

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2015年 / 137卷

基金：

中国国家自然科学基金;

关键词：

Paper-based analytical device; Chemiluminescence; Silver nanoparticle; Ofloxacin; LAB-ON-PAPER; LUMINOL CHEMILUMINESCENCE; GOLD NANOPARTICLES; HYDROGEN-PEROXIDE; HUMAN URINE; FLUORESCENCE DETECTION; COLORIMETRIC DETECTION; CARBON NANOTUBES; PLATFORM; SILVER;

D O I：

10.1016/j.saa.2014.09.059

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

Paper-based devices are biodegradable and have been used in diagnosis and environmental analysis field. In this work, a wax-printed paper-based analytical device combined with silver nanoparticles (AgNPs) catalyzed luminol chemiluminescence (CL) system for the determination of ofloxacin (OFLX) was presented. It was based on the enhancement of CL intensity of luminol-H2O2-OFLX system by AgNPs. Wax-printing fabrication technique was used to make the simple circle shaped paper device and large scale chips can be fabricated at the same time. Under the selected experimental conditions, a linear relationship was obtained between the CL intensity and the concentration of OFLX in the range from 1.0 x 10(-9) g/mL to 1.0 x 10(-6) g/mL with a detection limit of 3.0 x 10(-10) g/mL. This method has been successfully applied to the determination of OFLX in eyedrop samples. (C) 2014 Elsevier B.V. All rights reserved.

引用

页码：1298 / 1303

页数：6

共 44 条

[1] Chemiluminescence determination of some fluoroquinolone derivatives in pharmaceutical formulations and biological fluids using [Ru(bipy)23+]-Ce(IV) system [J].