First and short syntheses of biologically active, naturally occurring brominated mono- and dibenzyl phenols

被引:42
作者
Balaydin, Halis T. [1 ]
Akbaba, Yusuf [1 ]
Menzek, Abdullah [1 ]
Sahin, Ertan [1 ]
Goksu, Suleyman [1 ]
机构
[1] Ataturk Univ, Fac Sci, Dept Chem, TR-25240 Erzurum, Turkey
关键词
Bromination; bromophenols; red algae; natural product; synthesis; BROMOPHENOLS; INHIBITION; ETHERS;
D O I
10.3998/ark.5550190.0010.e07
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
First and short syntheses of biologically active, naturally occurring 3,4,6-tribromo-5-(2,3-dibromo-4,5-dihydroxybenzyl)benzene-1,2-diol 3, 3,4,6-tribromo-5-(2,3,6-tribromo-4,5-dihydroxybenzyl)benzene-1,2-diol 4 and 3,4-dibromo-5-[3-bromo-2-(2,3-dibromo-4,5-dihydroxybenzyl)-4,5-dihydroxybenzyl]benzene-1,2-diol 5 from the red alga were carried out.
引用
收藏
页码:75 / 87
页数:13
相关论文
共 28 条
[1]   Total Synthesis of the Biologically Active, Naturally Occurring 3,4-Dibromo-5-[2-bromo-3,4-dihydroxy-6-(methoxymethyl)benzyl]benzene-1,2-diol and Regioselective O-Demethylation of Aryl Methyl Ethers [J].
Akbaba, Yusuf ;
Balaydin, Halis Tuerker ;
Goksu, Sueleyman ;
Sahin, Ertan ;
Menzek, Abdullah .
HELVETICA CHIMICA ACTA, 2010, 93 (06) :1127-1135
[2]  
Albrecht M, 1996, SYNTHESIS-STUTTGART, P230
[3]  
[Anonymous], 1997, S HELXS 97 SHELXL 97
[4]   The alkylation of benzene in the presence of acid catalysts [J].
Burwell, RL ;
Archer, S .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1942, 64 :1032-1034
[5]   Highly brominated mono- and bis-phenols from the marine red alga Symphyocladia latiuscula with radical-scavenging activity [J].
Duan, Xiao-Juan ;
Li, Xiao-Ming ;
Wang, Bin-Gui .
JOURNAL OF NATURAL PRODUCTS, 2007, 70 (07) :1210-1213
[6]   Bromophenols from the red alga Rhodomela confervoides [J].
Fan, X ;
Xu, NJ ;
Shi, JG .
JOURNAL OF NATURAL PRODUCTS, 2003, 66 (03) :455-458
[7]  
FAN X, 2006, Patent No. 1853618
[8]   SYNTHESIS OF VARACIN, A CYTOTOXIC NATURALLY-OCCURRING BENZOPENTATHIEPIN ISOLATED FROM A MARINE ASCIDIAN [J].
FORD, PW ;
DAVIDSON, BS .
JOURNAL OF ORGANIC CHEMISTRY, 1993, 58 (17) :4522-4523
[9]  
GLOMBITZA K-W, 1985, Planta Medica, P437
[10]   NATURALLY-OCCURRING ORGANOHALOGEN COMPOUNDS - A SURVEY [J].
GRIBBLE, GW .
JOURNAL OF NATURAL PRODUCTS, 1992, 55 (10) :1353-1395