Velocities of weight, height and fat mass gain during potentially critical periods of growth are decisive for adult body composition

OBJECTIVES: To examine whether maximal velocities of weight, height and fat mass during potentially critical periods of growth were associated with body composition in young adulthood. SUBJECTS/METHODS: Analyses were performed on 277 female and 271 male participants of the DOrtmund Nutritional and Anthropometric Longitudinally Designed (DONALD) study with anthropometric measurements in young adulthood (18-25 years) as well as early life (0-2 years), mid-childhood (3-8 years) or puberty (9-15 years). Maximum growth velocities were calculated using the SuperImposition by Translation And Rotation (SITAR) routine or polynomial functions and related to adult fat mass index (FMI) and fat-free mass index (FFMI). RESULTS: In early life, faster weight gain was associated with a moderately higher FMI and FFMI in young adulthood in women only (P-trend = 0.01). In mid-childhood and puberty, weight and fat mass velocities were related to adult FMI and FFMI in both sexes (P-trend <= 0.002): relative differences between the highest and lowest tertiles of these growth velocities ranged 33-69% for adult FMI and 6-12% for adult FFMI. A higher mid-childhood height velocity was related to a modestly higher adult FMI in women only (P-trend = 0.0005). CONCLUSIONS: Faster gain in weight and body fat during mid-childhood and puberty appear to be particularly relevant for adult fat mass.