Synthesis of 9-phenol-substituted xanthenes by cascade O-insertion/1,6-conjugate addition of benzyne with ortho-hydroxyphenyl substituted para-quinone methides

被引：30
|
作者：
Li, Zhijuan [1 ]
Wang, Weihua [1 ]
Jian, Hui [1 ]
Li, Wenjuan [1 ]
Dai, Bin [1 ]
He, Lin [1 ]
机构：
[1] Shihezi Univ, Sch Chem & Chem Engn, Key Lab Green Proc Chem Engn Xinjiang Bingtuan, Shihezi 832000, Peoples R China
来源：
CHINESE CHEMICAL LETTERS | 2019年 / 30卷 / 02期
基金：
中国国家自然科学基金;
关键词：
Benzyne; para-Quinone methides; Xanthene; Cascade reaction; Cycloaddition; ENANTIOSELECTIVE 4+2 CYCLOADDITION; DIELS-ALDER REACTION; 1,6-CONJUGATE ADDITION; TANDEM REACTION; ARYNES; CYCLIZATION; XANTHONES; BEARING; ACCESS; THIOXANTHONES;
D O I：
10.1016/j.cclet.2018.04.003
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The cascade O-insertion/1,6 conjugate addition between benzynes and ortho-hydroxyphenyl substituted para-quinone methides has been reported, affording 9-phenol substituted xanthenes in 49%-84% yields. (C) 2018 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码：386 / 388
页数：3
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