The regulatory mechanisms of intragenic DNA methylation

被引:0
|
作者
Lee, Sun-Min [1 ]
Choi, Won-Young [2 ]
Lee, Jungwoo [2 ]
Kim, Young-Joon [1 ,2 ]
机构
[1] Yonsei Univ, Coll Life Sci & Technol, Dept Biochem, Seoul 120749, South Korea
[2] Yonsei Univ, Grad Sch, Dept Integrated Om Biomed Sci, Seoul 120749, South Korea
关键词
cancer; gene body methylation; splicing; transcriptional elongation; RNA-POLYMERASE-II; GENE BODY METHYLATION; CPG ISLANDS; HYPOMETHYLATION; ELONGATION; EXPRESSION; CELLS; METHYLTRANSFERASES; GENOME; TARGET;
D O I
10.2217/EPI.15.38
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
引用
收藏
页码:527 / 531
页数:5
相关论文
共 50 条
  • [21] Intragenic ATM methylation in peripheral blood DNA as a biomarker of breast cancer risk
    Brennan, Kevin
    Garcias-Closas, Montserrat
    Orr, Nicholas
    Fletcher, Olivia
    Jones, Michael
    Ashworth, Alan
    Swerdlow, Anthony
    Riboli, Elio
    Vineis, Paolo
    Dorronsosro, Mirren
    Clavel, Francoise
    Panico, Salvatore
    Onland-Moret, N. Charlotte
    Trichopoulos, Dimitrios
    Kaaks, Rudolf
    Khaw, Kay-Tee
    Brown, Robert
    Flanagan, James M.
    CANCER RESEARCH, 2012, 72
  • [22] DNA Methylation of Intragenic CpG Islands are Required for Differentiation from iPSC to NPC
    Choi, Won-Young
    Hwang, Ji-Hyun
    Cho, Ann-Na
    Lee, Andrew J.
    Lee, Jungwoo
    Jung, Inkyung
    Cho, Seung-Woo
    Kim, Lark Kyun
    Kim, Young-Joon
    STEM CELL REVIEWS AND REPORTS, 2020, 16 (06) : 1316 - 1327
  • [23] Intragenic ATM Methylation in Peripheral Blood DNA as a Biomarker of Breast Cancer Risk
    Brennan, Kevin
    Garcia-Closas, Montserrat
    Orr, Nick
    Fletcher, Olivia
    Jones, Michael
    Ashworth, Alan
    Swerdlow, Anthony
    Thorne, Heather
    Riboli, Elio
    Vineis, Paolo
    Dorronsoro, Miren
    Clavel-Chapelon, Francoise
    Panico, Salvatore
    Onland-Moret, N. Charlotte
    Trichopoulos, Dimitrios
    Kaaks, Rudolf
    Khaw, Kay-Tee
    Brown, Robert
    Flanagan, James M.
    CANCER RESEARCH, 2012, 72 (09) : 2304 - 2313
  • [24] A conserved role for intragenic DNA methylation in alternative pre-mRNA splicing
    Oberdoerffer, Shalini
    TRANSCRIPTION-AUSTIN, 2012, 3 (03): : 106 - 109
  • [25] Intragenic DNA methylation alters chromatin structure and elongation efficiency in mammalian cells
    Lorincz, MC
    Dickerson, DR
    Schmitt, M
    Groudine, M
    NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2004, 11 (11) : 1068 - 1075
  • [26] DNA Methylation of Intragenic CpG Islands are Required for Differentiation from iPSC to NPC
    Won-Young Choi
    Ji-Hyun Hwang
    Ann-Na Cho
    Andrew J Lee
    Jungwoo Lee
    Inkyung Jung
    Seung-Woo Cho
    Lark Kyun Kim
    Young-Joon Kim
    Stem Cell Reviews and Reports, 2020, 16 : 1316 - 1327
  • [27] The role and mechanisms of DNA methylation in the oocyte
    Sendzikaite, Gintare
    Kelsey, Gavin
    DNA METHYLATION, 2019, 63 (06): : 691 - 705
  • [28] Oncogenic mechanisms mediated by DNA methylation
    Laird, PW
    MOLECULAR MEDICINE TODAY, 1997, 3 (05): : 223 - 229
  • [29] Mechanisms of DNA methylation and demethylation in mammals
    Auclair, Ghislain
    Weber, Michael
    BIOCHIMIE, 2012, 94 (11) : 2202 - 2211
  • [30] Loss of CG Methylation in Marchantia polymorpha Causes Disorganization of Cell Division and Reveals Unique DNA Methylation Regulatory Mechanisms of Non-CG Methylation
    Ikeda, Yoko
    Nishihama, Ryuichi
    Yamaoka, Shohei
    Arteaga-Vazquez, Mario A.
    Aguilar-Cruz, Adolfo
    Grimanelli, Daniel
    Pogorelcnik, Romain
    Martienssen, Robert A.
    Yamato, Katsuyuki T.
    Kohchi, Takayuki
    Hirayama, Takashi
    Mathieu, Olivier
    PLANT AND CELL PHYSIOLOGY, 2018, 59 (12) : 2421 - 2431