A review on promising phytochemical, nutritional and glycemic control studies on Moringa oleifera Lam. in tropical and sub-tropical regions

被引:49
作者
Muhammad, Hafiz Irfan [1 ,2 ]
Asmawi, Mohd Zaini [1 ]
Khan, Nurzalina Abdul Karim [3 ]
机构
[1] Univ Sains Malaysia, Sch Pharmaceut Sci, Discipline Pharmacol, George Town 11800, Malaysia
[2] Univ Sargodha, Fac Pharm, Dept Pharmacol, Sargodha 48100, Pakistan
[3] Univ Sains Malaysia, Sch Pharmaceut Sci, Discipline Pharmaceut Technol, George Town 11800, Malaysia
关键词
INHIBITORY-ACTIVITY; GLUCOSE-TOLERANCE; DIABETES-MELLITUS; ALPHA-GLUCOSIDASE; MEDICINAL-PLANTS; HORSERADISH TREE; BETA-CELLS; IN-VITRO; EXTRACT; LEAVES;
D O I
10.1016/j.apjtb.2016.08.006
中图分类号
R188.11 [热带医学];
学科分类号
摘要
Plants have provided sources to find novel compounds. These plants are being used as therapeutic purposes since the birth of mankind. The traditional healers normally utilize medicinal plants as crude drugs while scientists using the folk claim as guides to explore medicinal plants. Moringa oleifera is a famous edible plant having therapeutic and nutritive values. The present study was designed to cumulate the research data regarding to what extent, phytochemical, nutritional and glycemic control studies has been explored using its different extracts. The articles indicated that the powder, aqueous, methanol and ethanol extracts of Moringa oleifera (leaves, pods, seeds, stem and root bark) have significant therapeutic herbal potential to treat diabetes mellitus. Collectively, the mechanism behind is intestinal glucose inhibition, insulin release as well as decrease in insulin resistance probably regeneration of beta-cells of pancreas, increase in glutathione and reduction in malondialdehyde. Conclusively, this article give descriptive information about antidiabetic effect, claimed marker compounds and proposed antihyperglycemic mechanism of a single plant. It can be suggested a potential herbal source to treat diabetes mellitus as being widely accepted by major population as nutrition and therapeutic agent.
引用
收藏
页码:896 / 902
页数:7
相关论文
共 79 条
[1]   Moringa oleifera leaf extract ameliorates alloxan-induced diabetes in rats by regeneration of β cells and reduction of pyruvate carboxylase expression [J].
Abd El Latif, Amira ;
El Bialy, Badr El Said ;
Mahboub, Hamada Dahi ;
Abd Eldaim, Mabrouk Attia .
BIOCHEMISTRY AND CELL BIOLOGY, 2014, 92 (05) :413-419
[2]  
Adeeyo A. O., 2013, Diabetologia Croatica, V42, P83
[3]  
Adejoh I.P., 2016, European J. Biotechnol. Biosci., V4, P14
[4]  
Adisakwattana S, 2011, EUR REV MED PHARMACO, V15, P803
[5]  
Aja P., 2013, INT J BIOCH REREV, V3, P248
[6]  
Ajibola M, 2014, BASIC SCI MED, V3, P37, DOI DOI 10.5923/J.MEDICINE.20140303.01
[7]   The Antidiabetic Effect of Low Doses of Moringa oleifera Lam. Seeds on Streptozotocin Induced Diabetes and Diabetic Nephropathy in Male Rats [J].
Al-Malki, Abdulrahman L. ;
El Rabey, Haddad A. .
BIOMED RESEARCH INTERNATIONAL, 2015, 2015
[8]  
Ali FT., 2015, INT J SCI ENG RES, V6, P1490
[9]   α-amylase inhibitory activity of some Malaysian plants used to treat diabetes;: with particular reference to Phyllanthus amarus [J].
Ali, Hasenah ;
Houghton, P. J. ;
Soumyanath, Amala .
JOURNAL OF ETHNOPHARMACOLOGY, 2006, 107 (03) :449-455
[10]  
Amer Diabet Assoc, 2010, DIABETES CARE, V33, pS62, DOI [10.2337/dc10-s062, 10.2337/dc09-S062]