Peculiarities of Using Stem Cells for Regeneration of the Bone and Cartilage Tissue

被引：0
|
作者：
Maiborodin, I. V. [1 ]
Shevela, A. I. [1 ]
Kolesnikov, I. S. [1 ]
Drovosekov, M. N. [1 ]
Toder, M. S. [1 ]
Shevela, A. A. [1 ]
Brombin, A. I. [1 ]
Beregovoy, E. A. [1 ]
机构：
[1] Russian Acad Sci, Inst Chem Biol & Fundamental Phys, Ctr New Med Technol, Siberian Div, Novosibirsk, Russia
来源：
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2011年 / 152卷 / 01期
关键词：
mesenchymal stem cells; cell technologies; regeneration of the bone and cartilaginous tissues; MESENCHYMAL STROMAL CELLS; INTERVERTEBRAL DISC; IN-VITRO; OSTEOCHONDRAL DEFECT; CHONDROGENIC DIFFERENTIATION; MARROW; TRANSPLANTATION; OSTEOGENESIS; INJECTION; MATRIX;
D O I：
10.1007/s10517-011-1468-8
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Scientific literature about the use of MSC contains clinical and experimental data on the efficiency of cell technologies for restoration of the osteoarticular apparatus. The use of MSC immobilized in the appropriate carriers and differentiation of these cells towards the bone cells and chondrocytes are of crucial importance. However, the use of MSC, both individual and in combination with other preparations and substances has a number of drawbacks and advantages. The absence of published reports on contraindications and complications of cell therapy is worthy of note, because the analysis of unsuccessful application of MSC will help to determine the indication for this treatment, and hence, to improve the efficiency of cell technologies in the future. Wider use of MSC in clinical practice and experimental studies for acceleration of reparative processes in the bone and cartilage tissue seems to be promising.
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页码：112 / 119
页数：8
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