Distribution and antifungal susceptibility of Candida species causing candidemia from 1996 to 1999

被引：80
|
作者：
Cheng, MF
Yu, KW
Tang, RB
Fan, YH
Yang, YL
Hsieh, KS
Ho, M
Lo, HJ [1 ]
机构：
[1] Natl Hlth Res Inst, Div Clin Res, Taipei, Taiwan
[2] Vet Gen Hosp, Dept Pediat, Kaohsiung, Taiwan
[3] Vet Gen Hosp, Dept Microbiol, Kaohsiung, Taiwan
[4] Vet Gen Hosp, Dept Pediat, Infect Dis Sect, Kaohsiung, Taiwan
[5] Natl Yang Ming Univ, Taipei 112, Taiwan
[6] Kaohsiung Med Univ, Kaohsiung, Taiwan
[7] Natl Chiao Tung Univ, Dept Biol Sci & Technol, Hsinchu, Taiwan
来源：
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2004年 / 48卷 / 01期
关键词：
Candida species; candidemia; antifungal susceptibility; resistance;
D O I：
10.1016/j.diagmicrobio.2003.08.002
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Susceptibilities to amphotericin B and fluconazole of 383 Candida species isolated from blood were determined. Candida albicans was the most common species (55.6%), followed by Candida parapsilosis (17.5%), Candida tropicalis (16.5%), Candida glabrata (5.2%), Candida guilliermondii (2.3%), and others (2.9%). All but three isolates, Candida ciferrii, C. tropicalis, and C glabrata, one each, were susceptible to amphotericin B. A total of 367 (95.8%) and 15 (4.2%) isolates were susceptible and susceptible-dose dependent to fluconazole, respectively. Only one isolate, a C glabrata, was resistant to fluconazole. Few patients (13%) having prior fluconazole treatments may explain the low rate of resistance to fluconazole in this study. (C) 2004 Elsevier Inc. All rights reserved.
引用
收藏
页码：33 / 37
页数：5
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