Synthesis of 2,6-diarylimidazo [2,1-b]-1,3,4-thiadiazoles 2 has been achieved by the reaction of alpha-haloketones with 2-amino-5-(2-pyridyl)-1,3,4-thiadiazole 1 or more conveniently by treating I directly with ketones in presence of NBS. Bromination of 2 furnished 5-bromo-2,6-diarylimidazo [2,1-b]-1,3,4-thiadiazoles 3. The antimicrobial activity of some of the compounds has been evaluated.