Block-copolymer-assisted synthesis of hydroxyapatite nanoparticles with high surface area and uniform size

被引：49

作者：

Huang, Yu-Tzu ^{[1
,2
]}

Imura, Masataka ^{[3
]}

Nemoto, Yoshihiro ^{[3
]}

Cheng, Chao-Hung ^{[4
]}

Yamauchi, Yusuke ^{[3
,5
,6
]}

机构：

[1] Chung Yuan Christian Univ, Dept Bioenvironm Engn, Chungli 32023, Taiwan

[2] Chung Yuan Christian Univ, R&D Ctr Membrane Technol, Chungli 32023, Taiwan

[3] Natl Inst Mat Sci, World Premier Int WPI Res Ctr Mat Nanoarchitecton, Tsukuba, Ibaraki 3050044, Japan

[4] Natl Taiwan Univ, Dept Chem Engn, Taipei 10617, Taiwan

[5] Waseda Univ, Fac Sci & Engn, Shinjuku Ku, Tokyo 1698555, Japan

[6] Japan Sci & Technol Agcy JST, Precursory Res Embryon Sci & Technol PRESTO, Kawaguchi, Saitama 3320012, Japan

来源：

SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS | 2011年 / 12卷 / 04期

关键词：

triblock copolymer F127; hydroxyapatite; nanoparticles; formation; coprecipitation method; calcium D-gluconate; potassium hydrogen phosphate; MESOSTRUCTURED CALCIUM PHOSPHATES; QUANTUM DOTS; SHELL; CORE;

D O I：

10.1088/1468-6996/12/4/045005

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

We report the synthesis of hydroxyapatite nanoparticles (HANPs) by the coprecipitation method using calcium D-gluconate and potassium hydrogen phosphate as the sources of calcium and phosphate ions, respectively, and the triblock copolymer F127 as a stabilizer. The HANPs were characterized using scanning electron microscopy, x-ray diffraction, and nitrogen adsorption/desorption isotherms. Removal of F127 by solvent extraction or calcination alters the structure of HANPs. The solvent-extracted HANPs were single crystals with their < 001 > axis oriented along the rod axis of the HANP, whereas the calcined HANPs contained two crystal phases that resulted in a spherical morphology. The calcined HANPs had much higher surface area (127m(2) g(-1)) than the solvent-extracted HANPs (44m(2) g(-1)).

引用

页数：6

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