Objective evaluation of anosmia and ageusia in COVID-19 patients: Single-center experience on 72 cases

被引:352
作者
Vaira, Luigi Angelo [1 ]
Deiana, Giovanna [2 ]
Fois, Alessandro Giuseppe [3 ]
Pirina, Pietro [3 ]
Madeddu, Giordano [4 ]
De Vito, Andrea [4 ]
Babudieri, Sergio [4 ]
Petrocelli, Marzia [5 ]
Serra, Antonello [6 ]
Bussu, Francesco [7 ]
Msn, Enrica Ligas [1 ]
Salzano, Giovanni [8 ]
De Riu, Giacomo [1 ]
机构
[1] Univ Hosp Sassari, Maxillofacial Surg Operat Unit, Viale San Pietro 43-B, Sassari 07100, Italy
[2] Univ Sassari, Dept Med Surg & Expt Sci, Sassari, Italy
[3] Univ Hosp Sassari, Resp Dis Operat Unit, Sassari, Italy
[4] Univ Hosp Sassari, Infect Dis Operat Unit, Sassari, Italy
[5] Bellaria & Maggiore Hosp, Maxillofacial Surg Operat Unit, Bologna, Italy
[6] Univ Hosp Sassari, Dept Surveillance & Prevent, Sassari, Italy
[7] Univ Hosp Sassari, Otolaryngol Operat Unit, Saaaari, Italy
[8] Univ Hosp Naples Federico II, Maxillofacial Surg Unit, Naples, Italy
来源
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2020年 / 42卷 / 06期
关键词
ageusia; anosmia; COVID-19; gustatory function; olfactory function;
D O I
10.1002/hed.26204
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Background The first European case series are detecting a very high frequency of chemosensitive disorders in COVID-19 patients, ranging between 19.4% and 88%. Methods Olfactory and gustatory function was objectively tested in 72 COVID-19 patients treated at University Hospital of Sassari. Results Overall, 73.6% of the patients reported having or having had chemosensitive disorders. Olfactory assessment showed variable degree hyposmia in 60 cases and anosmia in two patients. Gustatory assessment revealed hypogeusia in 33 cases and complete ageusia in one patient. Statistically significant differences in chemosensitive recovery were detected based on age and distance from the onset of clinical manifestations. Conclusion Olfactory and gustatory dysfunctions represent common clinical findings in COVID-19 patients. Otolaryngologists and head-neck surgeons must by now keep this diagnostic option in mind when evaluating cases of ageusia and nonspecific anosmia that arose suddenly and are not associated with rhinitis symptoms.
引用
收藏
页码:1252 / 1258
页数:7
相关论文
共 16 条
[1]   Evaluation of olfactory function in children with seasonal allergic rhinitis and its correlation with acoustic rhinometry [J].
Aksoy, Ceren ;
Elsurer, Cagdas ;
Artac, Hasibe ;
Bozkurt, Mete Kaan .
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, 2018, 113 :188-191
[2]  
CAIN WS, 1988, LARYNGOSCOPE, V98, P83
[3]   CLINICAL-EVALUATION OF OLFACTION [J].
CAIN, WS ;
GENT, J ;
CATALANOTTO, FA ;
GOODSPEED, RB .
AMERICAN JOURNAL OF OTOLARYNGOLOGY, 1983, 4 (04) :252-256
[4]   Age-Related Deficits in Taste and Smell [J].
Doty, Richard L. .
OTOLARYNGOLOGIC CLINICS OF NORTH AMERICA, 2018, 51 (04) :815-+
[5]   Isolated sudden onset anosmia in COVID-19 infection. A novel syndrome? [J].
Gane, Simon B. ;
Kelly, Christine ;
Hopkins, Claire .
RHINOLOGY, 2020, 58 (03) :299-301
[6]   Self-reported Olfactory and Taste Disorders in Patients With Severe Acute Respiratory Coronavirus 2 Infection: A Cross-sectional Study [J].
Giacomelli, Andrea ;
Pezzati, Laura ;
Conti, Federico ;
Bernacchia, Dario ;
Siano, Matteo ;
Oreni, Letizia ;
Rusconi, Stefano ;
Gervasoni, Cristina ;
Ridolfo, Anna Lisa ;
Rizzardini, Giuliano ;
Antinori, Spinello ;
Galli, Massimo .
CLINICAL INFECTIOUS DISEASES, 2020, 71 (15) :889-890
[7]  
Lechien JR, OLFACTORY GUSTATORY
[8]   Retronasal and orthonasal olfactory ability after laryngectomy [J].
Leon, Elizabeth A. ;
Catalanotto, Frank A. ;
Werning, John W. .
ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 2007, 133 (01) :32-36
[9]   Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury [J].
Liu, Yingxia ;
Yang, Yang ;
Zhang, Cong ;
Huang, Fengming ;
Wang, Fuxiang ;
Yuan, Jing ;
Wang, Zhaoqin ;
Li, Jinxiu ;
Li, Jianming ;
Feng, Cheng ;
Zhang, Zheng ;
Wang, Lifei ;
Peng, Ling ;
Chen, Li ;
Qin, Yuhao ;
Zhao, Dandan ;
Tan, Shuguang ;
Yin, Lu ;
Xu, Jun ;
Zhou, Congzhao ;
Jiang, Chengyu ;
Liu, Lei .
SCIENCE CHINA-LIFE SCIENCES, 2020, 63 (03) :364-374
[10]   ORAL SENSATION AND FUNCTION: A COMPARISON OF PATIENTS WITH INNERVATED RADIAL FOREARM FREE FLAP RECONSTRUCTION TO HEALTHY MATCHED CONTROLS [J].
Loewen, Irene J. ;
Boliek, Carol A. ;
Harris, Jeffrey ;
Seikaly, Hadi ;
Rieger, Jana M. .
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2010, 32 (01) :85-95