Zn(OAc)2•2H2O-Catalyzed Betti Base Synthesis under Solvent-free Conditions

被引：10

作者：

Alam, M. Mujahid ^{[1
]}

Bollikolla, Hari B. ^{[2
]}

Varala, Ravi ^{[3
]}

机构：

[1] King Khalid Univ, Coll Sci, Dept Chem, POB 9004, Abha 61413, Saudi Arabia

[2] Acharya Nagarjuna Univ, Dept Chem, Guntur 522510, Andhra Pradesh, India

[3] Scrips Pharma, Hyderabad 500076, Telangana, India

来源：

LETTERS IN ORGANIC CHEMISTRY | 2022年 / 19卷 / 01期

关键词：

Betti base; zinc acetate dehydrate (Zn(OAc)(2)center dot 2H(2)O); catalysis; multicomponent synthesis; beta-naphthol; amines and solvent-free conditions; ZINC ACETATE; EFFICIENT; POT; AMINOALKYLATION; INHIBITION; CATALYST;

D O I：

10.2174/1570178618666210616155257

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Zn(OAc)(2)center dot 2H(2)O-catalyzed one-pot multicomponent reaction of Betti bases using beta-naphthol, aldehydes, and amines, under neat conditions in moderate to excellent yields (68-96%) is reported in this study. This synthetic protocol offers several advantages, such as operational simplicity, shorter reaction period, high yields, and easy work-up procedures.

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收藏

页码：14 / 18

页数：5

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