Review on surface modification of nanocarriers to overcome diffusion limitations: An enzyme immobilization aspect

被引：76

作者：

Malar, Carlin Geor ^{[1
]}

Seenuvasan, Muthulingam ^{[2
]}

Kumar, Kannaiyan Sathish ^{[3
]}

Kumar, Anil ^{[4
]}

Parthiban, R. ^{[3
]}

机构：

[1] Rajalakshmi Engn Coll, Dept Biotechnol, Thandalam, India

[2] Hindusthan Coll Engn & Technol, Dept Chem Engn, Coimbatore, Tamil Nadu, India

[3] SSN Coll Engn, Dept Chem Engn, Kalavakkam, Tamil Nadu, India

[4] CSIR Cent Salt & Marine Chem Res Inst, Analyt & Environm Sci Div, Bhavnagar, Gujarat, India

来源：

BIOCHEMICAL ENGINEERING JOURNAL | 2020年 / 158卷

关键词：

Catalytic; Biochemical reaction; Enzyme; Immobilization; Diffusion limitations; ORGANIC-INORGANIC HYBRID; MAGNETIC NANOPARTICLES; HETEROGENEOUS CATALYST; GOLD NANOPARTICLES; DEGRADATION; POLYMER; MINERALIZATION; HYDROGELS; BEADS; DETOXIFICATION;

D O I：

10.1016/j.bej.2020.107574

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Immobilized enzymes are widely used in the industries for various biochemical reactions in order to gain the benefits of higher stability and reusability. Emerging trends of nanotechnology in immobilization have extended their major applications as carriers for the enzymes. Nanomaterials exhibit different, unique properties like high surface area to volume ratio, high reactivity, catalytic activity, rigidity, solubility, semi-conductivity and size dependent optical properties. But it is a great challenge for the nanomaterials to exhibit these unique properties completely in the reaction system due to the diffusion limitations. This review focusses on the involvement of diffusion and diffusion limitations in various catalytic reactions, methods to evaluate diffusion limitations and different strategies to overcome. This review can be a different perspective towards the biochemical reactions and can provide information to carry out the enzyme substrate reaction processes using nanomaterials as carriers overcoming diffusion limitations.

引用

页数：8

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