The prevailing paradigms ascribe the initiation of immune surveillance to the detection of foreign or inflammatory 'danger' signals. However, new work indicates that immune cells can detect early signs of cellular dysregulation that precede tumorigenesis, even in the absence of non-self signals and/or inflammation.
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Washington Univ, Sch Med, Ctr Immunol, Dept Pathol & Immunol, St Louis, MO 63110 USAWashington Univ, Sch Med, Ctr Immunol, Dept Pathol & Immunol, St Louis, MO 63110 USA
Dunn, GP
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Old, LJ
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机构:Washington Univ, Sch Med, Ctr Immunol, Dept Pathol & Immunol, St Louis, MO 63110 USA
Old, LJ
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Schreiber, RD
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机构:Washington Univ, Sch Med, Ctr Immunol, Dept Pathol & Immunol, St Louis, MO 63110 USA
机构:Guys Kings St Thomas Med Sch, Peter Gorer Dept Immunobiol, London SE1 9RT, England
Girardi, M
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Oppenheim, DE
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机构:Guys Kings St Thomas Med Sch, Peter Gorer Dept Immunobiol, London SE1 9RT, England
Oppenheim, DE
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Steele, CR
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Steele, CR
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Lewis, JM
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机构:Guys Kings St Thomas Med Sch, Peter Gorer Dept Immunobiol, London SE1 9RT, England
Lewis, JM
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Glusac, E
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机构:Guys Kings St Thomas Med Sch, Peter Gorer Dept Immunobiol, London SE1 9RT, England
Glusac, E
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Filler, R
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Filler, R
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Hobby, P
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机构:Guys Kings St Thomas Med Sch, Peter Gorer Dept Immunobiol, London SE1 9RT, England
Hobby, P
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Sutton, B
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机构:Guys Kings St Thomas Med Sch, Peter Gorer Dept Immunobiol, London SE1 9RT, England
Sutton, B
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Tigelaar, RE
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机构:Guys Kings St Thomas Med Sch, Peter Gorer Dept Immunobiol, London SE1 9RT, England
Tigelaar, RE
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Hayday, AC
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Guys Kings St Thomas Med Sch, Peter Gorer Dept Immunobiol, London SE1 9RT, EnglandGuys Kings St Thomas Med Sch, Peter Gorer Dept Immunobiol, London SE1 9RT, England
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Washington Univ, Sch Med, Ctr Immunol, Dept Pathol & Immunol, St Louis, MO 63110 USAWashington Univ, Sch Med, Ctr Immunol, Dept Pathol & Immunol, St Louis, MO 63110 USA
Dunn, GP
;
Old, LJ
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机构:Washington Univ, Sch Med, Ctr Immunol, Dept Pathol & Immunol, St Louis, MO 63110 USA
Old, LJ
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Schreiber, RD
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机构:Washington Univ, Sch Med, Ctr Immunol, Dept Pathol & Immunol, St Louis, MO 63110 USA
机构:Guys Kings St Thomas Med Sch, Peter Gorer Dept Immunobiol, London SE1 9RT, England
Girardi, M
;
Oppenheim, DE
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机构:Guys Kings St Thomas Med Sch, Peter Gorer Dept Immunobiol, London SE1 9RT, England
Oppenheim, DE
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Steele, CR
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机构:Guys Kings St Thomas Med Sch, Peter Gorer Dept Immunobiol, London SE1 9RT, England
Steele, CR
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Lewis, JM
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机构:Guys Kings St Thomas Med Sch, Peter Gorer Dept Immunobiol, London SE1 9RT, England
Lewis, JM
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Glusac, E
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机构:Guys Kings St Thomas Med Sch, Peter Gorer Dept Immunobiol, London SE1 9RT, England
Glusac, E
;
Filler, R
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机构:Guys Kings St Thomas Med Sch, Peter Gorer Dept Immunobiol, London SE1 9RT, England
Filler, R
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Hobby, P
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机构:Guys Kings St Thomas Med Sch, Peter Gorer Dept Immunobiol, London SE1 9RT, England
Hobby, P
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Sutton, B
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机构:Guys Kings St Thomas Med Sch, Peter Gorer Dept Immunobiol, London SE1 9RT, England
Sutton, B
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Tigelaar, RE
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机构:Guys Kings St Thomas Med Sch, Peter Gorer Dept Immunobiol, London SE1 9RT, England
Tigelaar, RE
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Hayday, AC
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Guys Kings St Thomas Med Sch, Peter Gorer Dept Immunobiol, London SE1 9RT, EnglandGuys Kings St Thomas Med Sch, Peter Gorer Dept Immunobiol, London SE1 9RT, England