Combined detection of Chlamydia trachomatis-specific antibodies against the 10 and 60-kDa heat shock proteins as a diagnostic tool for tubal factor infertility:: Results from a case-control study in Cameroon

被引：12

作者：

Dadamessi, I

Eb, F

Betsou, F

机构：

[1] Ctr Hosp Univ Amiens, F-80480 Salouel, France

[2] Univ Amiens, Ctr Hosp, Rene Laennec, F-80480 Salouel, France

[3] Ctr Hosp Univ Amiens, Dept Bacteriol & Hyg, Amiens, France

来源：

FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY | 2005年 / 45卷 / 01期

关键词：

Chlamydia trachomatis; tubal infertility; heat shock proteins;

D O I：

10.1016/j.femsim.2005.01.009

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A case-control study was conducted to determine the diagnostic value of Chlamydia trachomatis-associated anti-Chsp10 and/or anti-Chsp60 antibodies in the detection of secondary infertility. There were significant associations between C trachomatis infection and infertility (p < 0.01), and between C trachomatis-specific anti-Chsp10 or anti-Chsp60 antibodies and secondary infertility (p < 0.001). A significant correlation was found between anti-Clisp10 and anti-Chsp60 titers (p < 0.01). The detection of either C trachomatis-associated anti-Chsp10 or anti-Chsp60 antibodies cumulatively allowed specific diagnosis of secondary infertility (57.4% sensitivity, 75.5% specificity). (c) 2005 Federation of European Microbiological Societies. Published by Elsevier B.V. All rights reserved.

引用

页码：31 / 35

页数：5

共 21 条

[1] The prevalence of Chlamydia trachomatis in fresh tissue specimens from patients with ectopic pregnancy or tubal factor infertility as determined by PCR and in-situ hybridisation [J].