Effects of anti-aging interventions on intestinal microbiota

被引：61

作者：

Du, Yanjiao ^{[1
]}

Gao, Yue ^{[1
]}

Zeng, Bo ^{[1
]}

Fan, Xiaolan ^{[1
]}

Yang, Deying ^{[1
]}

Yang, Mingyao ^{[1
]}

机构：

[1] Sichuan Agr Univ, Anim Genet Resources Explorat & Innovat Key Lab S, Chengdu 611130, Sichuan, Peoples R China

来源：

GUT MICROBES | 2021年 / 13卷 / 01期

基金：

中国国家自然科学基金;

关键词：

Intestinal microbiota; aging; dietary intervention; exercise; drugs; bacteriotherapy; INTERNATIONAL SCIENTIFIC ASSOCIATION; GUT MICROBIOTA; LIFE-SPAN; AKKERMANSIA-MUCINIPHILA; CALORIC RESTRICTION; CONSENSUS STATEMENT; DIETARY RESTRICTION; MEDITERRANEAN DIET; ACARBOSE TREATMENT; METABOLIC SYNDROME;

D O I：

10.1080/19490976.2021.1994835

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Identifying ways to deal with the challenges presented by aging is an urgent task, as we are facing an aging society. External factors such as diet, exercise and drug therapy have proven to be major elements in controlling healthy aging and prolonging life expectancy. More recently, the intestinal microbiota has also become a key factor in the anti-aging process. As the intestinal microbiota changes with aging, an imbalance in intestinal microorganisms can lead to many age-related degenerative diseases and unhealthy aging. This paper reviews recent research progress on the relationship between intestinal microorganisms and anti-aging effects, focusing on the changes and beneficial effects of intestinal microorganisms under dietary intervention, exercise and drug intervention. In addition, bacteriotherapy has been used to prevent frailty and unhealthy aging. Most of these anti-aging approaches improve the aging process and age-related diseases by regulating the homeostasis of intestinal flora and promoting a healthy intestinal environment. Intervention practices based on intestinal microorganisms show great potential in the field of anti-aging medicine.

引用

页数：18

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