Integrative Psychotherapeutic Nursing Home Program to Reduce Multiple Psychiatric Symptoms of Cognitively Impaired Patients and Caregiver Burden: Randomized Controlled Trial

被引:32
作者
Bakker, Ton J. E. M. [1 ,2 ,3 ]
Duivenvoorden, Hugo J. [1 ,4 ]
van der Lee, Jacqueline [1 ]
Rikkert, Marcel G. M. Olde [5 ]
Beekman, Aartjan T. F. [3 ,6 ,7 ]
Ribbe, Miel W. [2 ,3 ]
机构
[1] Argos Zorggrp, Dept R&D, Psychiat Skilled Nursing Home DrieMaasStede, NL-3123 AX Schiedam, Netherlands
[2] Vrije Univ Amsterdam, EMGO Inst Hlth & Care Res, VU Dept Nursing Home Med, Amsterdam, Netherlands
[3] Vrije Univ Amsterdam, Med Ctr, Amsterdam, Netherlands
[4] Erasmus Univ, Dept Med Psychol & Psychotherapy, Rotterdam, Netherlands
[5] Radboud Univ Nijmegen, Med Ctr, Dept Geriatr, NL-6525 ED Nijmegen, Netherlands
[6] Vrije Univ Amsterdam, EMGO Inst Hlth & Care Res, Dept Psychiat, Amsterdam, Netherlands
[7] Vrije Univ Amsterdam, EMGO Inst Hlth & Care Res, GGZ Buitenamstel, Amsterdam, Netherlands
关键词
Nursing home; cognitive impairment; neuropsychiatric symptoms; psychiatry; BPSD; psychotherapy; LATE-LIFE DEPRESSION; LONG-TERM-CARE; NEUROPSYCHIATRIC SYMPTOMS; ALZHEIMER-DISEASE; PSYCHOLOGICAL SYMPTOMS; COLLABORATIVE CARE; OLDER-ADULTS; PSYCHOSOCIAL APPROACH; BEHAVIORAL SYMPTOMS; MISSING DATA;
D O I
10.1097/JGP.0b013e3181eafdc6
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Objective: To test the effectiveness of an integrative psychotherapeutic nursing home program (integrative reactivation and rehabilitation [IRR]) to reduce multiple neuropsychiatry symptoms (MNPS) of cognitively impaired patients and caregiver burden (CB). Design: Randomized controlled trial. Setting: Psychiatric-skilled nursing home (IRR) and usual care (UC), consisting of different types of nursing home care at home or in an institution. Participants: N = 168 (81 IRR and 87 UC). Patients had to meet classification of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition for dementia, amnestic disorders, or other cognitive disorders. Further inclusion criteria: Neuropsychiatric Inventory (NPI) >= 3; Mini-Mental State Examination >= 18 and <= 27; and Barthel Index (BI) >= 5 and <= 19. Intervention: IRR consisted of a person-oriented integrative psychotherapeutic nursing home program to reduce MNPS of the patient and CB. UC consisted of different types of nursing home care at home or in an institution, mostly emotion oriented. Measurements: Primary outcome variable was MNPS (number and sum-severity of NPI). Furthermore, burden and competence of caregiver were also measured. Assessments: T1 (inclusion), T2 (end of treatment), T3 (after 6 months of follow-up). Cohen's d (Cd) was calculated for mean differences (intention to treat). For confounding, repeated measurement modeling (random regression modeling [RRM]) was applied. Results: In the short term from the perspective of the caregiver, IRR showed up to 34% surplus effects on MNPS of the patients; NPI symptoms: 1.31 lower (Cd, -0.53); and NPI sum-severity: 11.16 lower (Cd, -0.53). In follow-up, the effects were sustained. However, from the perspective of the nursing team, these effects were insignificant, although the trend was in the same direction and correlated significantly with the caregiver results over time (at T3: r = 0.48). In addition, IRR showed surplus effects (up to 36%) on burden and competence of caregiver: NPI emotional distress: 3.78 (Cd, -0.44); CB: 17.69 (Cd, -0.63) lower; and Competence: 6.26 (Cd, 0.61) higher. In follow-up, the effects increased up to 50%. RRM demonstrated that the effects were stable. Conclusion : From the perspective of the caregiver, IRR was significantly more effective than UC to reduce MNPS in cognitively impaired patients and CB. In follow-up, the effect on CB even increased. However, from the perspective of the nursing team, the effects on MNPS were statistically insignificant. Nevertheless, the trend was in the same direction and correlated significantly with the caregiver results over time. Further research is needed, preferably using a blinded randomized controlled trial. (Am J Geriatr Psychiatry 2011; 19:507-520)
引用
收藏
页码:507 / 520
页数:14
相关论文
共 67 条
[1]   The course of neuropsychiatric symptoms in dementia. Part II: relationships among behavioural sub-syndromes and the influence of clinical variables [J].
Aalten, P ;
de Vugt, ME ;
Jaspers, N ;
Jolles, J ;
Verhey, FRJ .
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, 2005, 20 (06) :531-536
[2]   Neuropsychiatric syndromes in dementia - Results from the European Alzheimer Disease Consortium: Part I [J].
Aalten, Pauline ;
Verhey, Frans R. J. ;
Boziki, Marina ;
Bullock, Roger ;
Byrne, Eleanor Jane ;
Camus, Vincent ;
Caputo, Miriam ;
Collins, Debby ;
De Deyn, Peter Paul ;
Elina, Kazi ;
Frisoni, Giovanni ;
Girtler, Nicola ;
Holmes, Clive ;
Hurt, Catherine ;
Marriott, Anna ;
Mecocci, Patrizia ;
Nobili, Flavio ;
Ousset, Pierre Jean ;
Reynish, Emma ;
Salmon, Eric ;
Tsolaki, Magda ;
Vellas, Bruno ;
Robert, Philippe H. .
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, 2007, 24 (06) :457-463
[3]  
[Anonymous], 1988, STAT ANAL BEHAV SCI
[4]  
Bakker TJE, 2001, INT J GERIATR PSYCH, V16, P1, DOI 10.1002/1099-1166(200101)16:1<1::AID-GPS254>3.0.CO
[5]  
2-5
[6]   Palliative care in chronic psycho-geriatrics: A case-study [J].
Bakker, TJEM .
PATIENT EDUCATION AND COUNSELING, 2000, 41 (01) :107-113
[7]   Prevalence of psychiatric function disorders in psychogeriatric patients at referral to nursing home care - the relation to cognition, activities of daily living and general details [J].
Bakker, TJEM ;
Duivenvoorden, HJ ;
van der Lee, J ;
Trijsburg, RW .
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, 2005, 20 (04) :215-224
[8]   TOP CITED PAPERS IN INTERNATIONAL PSYCHOGERIATRICS: 6a. QUALITY OF LIFE FOR PEOPLE WITH DEMENTIA LIVING IN RESIDENTIAL AND NURSING HOME CARE: THE IMPACT OF PERFORMANCE ON ACTIVITIES OF DAILY LIVING, BEHAVIORAL AND PSYCHOLOGICAL SYMPTOMS, LANGUAGE SKILLS, AND PSYCHOTROPIC DRUGS [J].
Ballard, C. ;
Margallo-Lana, M. ;
O'Brien, J. T. ;
James, I. ;
Howard, R. ;
Fossey, J. .
INTERNATIONAL PSYCHOGERIATRICS, 2009, 21 (06) :1026-1030
[9]   Brief Psychosocial Therapy for the Treatment of Agitation in Alzheimer Disease (The CALM-AD Trial) [J].
Ballard, Clive ;
Brown, Richard ;
Fossey, Jane ;
Douglas, Simon ;
Bradley, Paul ;
Hancock, Judith ;
James, Ian A. ;
Juszczak, Edmund ;
Bentham, Peter ;
Burns, Alistair ;
Lindesay, James ;
Jacoby, Robin ;
O'Brien, John ;
Bullock, Roger ;
Johnson, Tony ;
Holmes, Clive ;
Howard, Robert .
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY, 2009, 17 (09) :726-733
[10]   Predictors of Preventable Nursing Home Hospitalizations: The Role of Mental Disorders and Dementia [J].
Becker, Marion A. ;
Boaz, Timothy L. ;
Andel, Ross ;
Gum, Amber M. ;
Papadopoulos, Airia S. .
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY, 2010, 18 (06) :475-482