Adolescent obesity and bariatric surgery

被引:8
作者
Levitsky, Lynne L. [1 ]
Misra, Madhusmita [1 ]
Boepple, Paul A. [1 ,2 ]
Hoppin, Alison G. [2 ,3 ]
机构
[1] Harvard Univ, Sch Med, Massachusetts Gen Hosp, Pediat Endocrine Unit, Boston, MA 02114 USA
[2] Harvard Univ, Sch Med, Massachusetts Gen Hosp, Pediat Weight Ctr, Boston, MA 02114 USA
[3] Harvard Univ, Sch Med, Massachusetts Gen Hosp, Pediat GI Unit, Boston, MA 02114 USA
关键词
adolescent obesity; bariatric surgery; endocrine effects; outcomes; weight loss; GASTRIC BYPASS-SURGERY; VERTICAL BANDED GASTROPLASTY; NONALCOHOLIC FATTY LIVER; BODY-MASS INDEX; AMBULATORY BLOOD-PRESSURE; TYPE-2; DIABETES-MELLITUS; GLUCAGON-LIKE PEPTIDE-1; INTIMA-MEDIA THICKNESS; QUALITY-OF-LIFE; METABOLIC SYNDROME;
D O I
10.1097/MED.0b013e32832101ff
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose of review Examines the effects of bariatric surgery on adolescent obesity. Recent findings The risks and outcomes of bariatric surgery in adolescence are presently being defined and may be somewhat different from those in adults. Adolescents may have a greater risk of weight regain, and greater risk of noncompliance to treatment after surgery. However, long-term outcomes are not yet available, and the underlying metabolic benefits appear to be substantial and similar to those of adults. Summary Morbid obesity in adolescents has severe acute and chronic complications. Bariatric surgery in adolescents seems as well tolerated as in adults when performed in centers with appropriate experience and adequate surgical volume. The pathophysiologic implications of bariatric surgery are profound. A better understanding of the mechanisms leading to postsurgical improvement in insulin resistance and weight loss could lead to the development of other therapies to achieve the same effects with lesser morbidities.
引用
收藏
页码:37 / 44
页数:8
相关论文
共 117 条
  • [1] Abbasi Ali A, 2007, Endocr Pract, V13, P131
  • [2] Laparoscopic adjustable gastric banding in adolescent: safety and efficacy
    Al-Oahtani, Aayed R.
    [J]. JOURNAL OF PEDIATRIC SURGERY, 2007, 42 (05) : 894 - 897
  • [3] Resolution of diabetes mellitus and metabolic syndrome following Roux-en-Y gastric bypass and a variant of biliopancreatic diversion in patients with morbid obesity
    Alexandrides, Theodore K.
    Skroubis, George
    Kalfarentzos, Fotis
    [J]. OBESITY SURGERY, 2007, 17 (02) : 176 - 184
  • [4] Best practice guidelines in pediatric/adolescent weight loss surgery
    Apovian, CM
    Baker, C
    Ludwig, DS
    Hoppin, AG
    Hsu, G
    Lenders, C
    Pratt, JSA
    Forse, RA
    O'Brien, A
    Tarnoff, M
    [J]. OBESITY RESEARCH, 2005, 13 (02): : 274 - 282
  • [5] Childhood body-mass index and the risk of coronary heart disease in adulthood
    Baker, Jennifer L.
    Olsen, Lina W.
    Sorensen, Thorkild I. A.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (23) : 2329 - 2337
  • [6] Peptide YY(1-36) and peptide YY(3-36): Part I. Distribution, release and actions
    Ballantyne, GH
    [J]. OBESITY SURGERY, 2006, 16 (05) : 651 - 658
  • [7] Bariatric surgery in adolescents: For treatment failures or health care system failures?
    Barlow, SE
    [J]. PEDIATRICS, 2004, 114 (01) : 252 - 253
  • [8] Bluher Susann, 2007, Curr Opin Endocrinol Diabetes Obes, V14, P458, DOI 10.1097/MED.0b013e3282f1cfdc
  • [9] ANOREXIA-NERVOSA - IMMATURITY OF 24-HOUR LUTEINIZING-HORMONE SECRETORY PATTERN
    BOYAR, RM
    KATZ, J
    FINKELSTEIN, JW
    KAPEN, S
    WEINER, H
    WEITZMAN, ED
    HELLMAN, L
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1974, 291 (17) : 861 - 865
  • [10] Bariatric surgery: A systematic review and meta-analysis
    Buchwald, H
    Avidor, Y
    Braunwald, E
    Jensen, MD
    Pories, W
    Fahrbach, K
    Schoelles, K
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2004, 292 (14): : 1724 - 1737