A novel Zn-catalyzed hydroamination of propargylamides: a general synthesis of di- and tri-substituted imidazoles

被引：32
作者：
Pews-Davtyan, Anahit [1 ]
Beller, Matthias [1 ]
机构：
[1] Univ Rostock eV, Leibniz Inst Katalyse, D-18059 Rostock, Germany
来源：
CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 07期
关键词：
ONE-POT SYNTHESIS; TERMINAL ALKYNES; INTERMOLECULAR HYDROAMINATION; MILD CONDITIONS; C-C; DERIVATIVES; CYCLIZATION; FUNCTIONALIZATION; 1H-IMIDAZOLES; HETEROCYCLES;
D O I：
10.1039/c0cc04625f
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Starting from commercially available amines and propargyl-amides a variety of substituted imidazoles were synthesized via a novel hydroamination-cyclization sequence. The target compounds are obtained in good to excellent yields in the presence of catalytic amounts of zinc triflate.
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收藏
页码：2152 / 2154
页数：3
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