The international EAACI/GA2LEN/EuroGuiDerm/APAAACI guideline for the definition, classification, diagnosis, and management of urticaria

被引：711

作者：

Zuberbier, Torsten ^{[1
,2
,3
,4
]}

Abdul Latiff, Amir Hamzah ^{[5
]}

Abuzakouk, Mohamed ^{[6
]}

Aquilina, Susan ^{[7
]}

Asero, Riccardo ^{[8
]}

Baker, Diane ^{[9
]}

Ballmer-Weber, Barbara ^{[10
,11
]}

Bangert, Christine ^{[12
]}

Ben-Shoshan, Moshe ^{[13
]}

Bernstein, Jonathan A. ^{[14
]}

Bindslev-Jensen, Carsten ^{[15
,16
,17
]}

Brockow, Knut ^{[18
]}

Brzoza, Zenon ^{[19
]}

Chong Neto, Herberto Jose ^{[20
]}

Church, Martin K. ^{[1
,2
,3
,4
,21
]}

Criado, Paulo R. ^{[22
]}

Danilycheva, Inna V. ^{[23
]}

Dressler, Corinna ^{[2
,3
,4
,24
]}

Ensina, Luis Felipe ^{[25
]}

Fonacier, Luz ^{[26
]}

Gaskins, Matthew ^{[2
,3
,4
,24
]}

Gaspar, Krisztian ^{[27
]}

Gelincik, Asli ^{[28
]}

Gimenez-Arnau, Ana ^{[29
,30
]}

Godse, Kiran ^{[31
]}

Goncalo, Margarida ^{[32
,33
]}

Grattan, Clive ^{[34
]}

Grosber, Martine ^{[35
]}

Hamelmann, Eckard ^{[36
]}

Hebert, Jacques ^{[37
]}

Hide, Michihiro ^{[38
,39
]}

Kaplan, Allen ^{[40
]}

Kapp, Alexander ^{[41
]}

Kessel, Aharon ^{[42
,43
]}

Kocaturk, Emek ^{[44
]}

Kulthanan, Kanokvalai ^{[45
]}

Larenas-Linnemann, Desiree ^{[46
]}

Lauerma, Antti ^{[47
,48
]}

Leslie, Tabi A. ^{[49
]}

Magerl, Markus ^{[1
,2
,3
,4
,50
]}

Makris, Michael ^{[51
]}

Meshkova, Raisa Y. ^{[52
]}

Metz, Martin ^{[1
,2
,3
,4
,50
]}

Micallef, Daniel ^{[7
]}

Mortz, Charlotte G. ^{[53
,54
,55
]}

Nast, Alexander ^{[2
,3
,4
,24
]}

Oude-Elberink, Hanneke ^{[56
]}

Pawankar, Ruby ^{[57
]}

Pigatto, Paolo D. ^{[58
]}

Ratti Sisa, Hector ^{[59
]}

机构：

[1] Charite Univ Med Berlin, Comprehens Allergy Ctr Charite, Hindenburgdamm 30, D-12203 Berlin, Germany

[2] Free Univ Berlin, Berlin, Germany

[3] Humboldt Univ, Berlin, Germany

[4] Berlin Inst Hlth, Berlin, Germany

[5] Pantai Hosp Kuala Lumpur, Allergy & Immunol Ctr, Kuala Lumpur, Malaysia

[6] Cleveland Clin Abu Dhabi, Dept Allergy & Immunol, Resp Inst, Abu Dhabi, U Arab Emirates

[7] Mater Dei Hosp, Dept Dermatol, Msida, Malta

[8] Clin San Carlo, Ambulatorio Allergol, Paderno Dugnano, MI, Italy

[9] Baker Allergy Asthma & Dermatol, Portland, OR USA

[10] Kantonsspital St Gallen, Clin Dermatol & Allergol, St Gallen, Switzerland

[11] Univ Hosp Zurich, Dept Dermatol, Zurich, Switzerland

[12] Med Univ Vienna, Dept Dermatol, Vienna, Austria

[13] McGill Univ, Montreal Childrens Hosp, Dept Pediat, Div Allergy Immunol & Dermatol, Montreal, PQ, Canada

[14] Univ Cincinnati, Phys Immunol Res Ctr, Cincinnati, OH USA

[15] Odense Univ Hosp, Dept Dermatol, Odense, Denmark

[16] Odense Univ Hosp, Allergy Ctr, Odense, Denmark

[17] Univ Southern Denmark, Odense, Denmark

[18] Tech Univ Munich, Fac Med, Dept Dermatol & Allergy Biederstein, Munich, Germany

[19] Univ Opole, Dept Internal Dis, Div Allergol, Opole, Poland

[20] Univ Fed Parana, Dept Pediat, Div Allergy & Immunol, Curitiba, Parana, Brazil

[21] Univ Southampton, Southampton, Hants, England

[22] Alergoskin UCARE, Ctr Univ FMABC, Soc Brasileira Dermatol SBD, Santo Andre, SP, Brazil

[23] Fed Med Biol Agcy Russia, Inst Immunol, Natl Res Ctr, Dept Allergol & Immunotherapy, Moscow, Russia

[24] Charite Univ Med Berlin, Dept Dermatol Venereol & Allergy, Div Evidence Based Med, Berlin, Germany

[25] Univ Fed Sao Paulo, Dept Pediat, Div Allergy Clin Immunol & Rheumatol, Sao Paulo, Brazil

[26] NYU, Long Isl Sch Med, New York, NY USA

[27] Univ Debrecen, Fac Med, Dept Dermatol, Div Dermatol Allergol, Debrecen, Hungary

[28] Istanbul Univ, Istanbul Fac Med, Dept Internal Med, Div Immunol & Allerg Dis, Istanbul, Turkey

[29] Univ Autonoma Barcelona, Inst Mar Invest Med, Hosp Mar, Dept Dermatol, Barcelona, Spain

[30] Univ Pompeu Fabra, Barcelona, Spain

[31] DY Patil Univ, Sch Med, Dept Dermatol, Navi Mumbai, India

[32] Univ Coimbra, Coimbra Univ Hosp, Dept Dermatol, Coimbra, Portugal

[33] Univ Coimbra, Fac Med, Coimbra, Portugal

[34] Guys Hosp, St Johns Inst Dermatol, London, England

[35] Vrije Univ Brussel VUB, Univ Ziekenhuis Brussel UZ Brussel, Dept Dermatol, Brussels, Belgium

[36] Univ Bielefeld, Univ Hosp OWL, Childrens Ctr Bethel, Dept Pediat, Bielefeld, Germany

[37] CHU Quebec, CHU Laval, Serv Allergie, Quebec City, PQ, Canada

[38] Hiroshima Univ, Dept Dermatol, Hiroshima, Japan

[39] Hiroshima Citizens Hosp, Dept Dermatol, Hiroshima, Japan

[40] Med Univ South Carolina, Div Pulm & Crit Care Med, Allergy & Clin Immunol, Dept Med, Charleston, SC 29425 USA

[41] Hannover Med Sch MHH, Dept Dermatol & Allergy, Hannover, Germany

[42] Technion, Bnai Zion Med Ctr, Div Allergy & Clin Immunol, Haifa, Israel

[43] Technion, Bruce & Ruth Rappaport Fac Med, Haifa, Israel

[44] Koc Univ, Sch Med, Dept Dermatol, Istanbul, Turkey

[45] Mahidol Univ, Siriraj Hosp, Dept Dermatol, Fac Med, Bangkok, Thailand

[46] Hosp Med Sur, Mexico City, DF, Mexico

[47] Univ Helsinki, Inflammat Ctr, Dept Dermatol Allergol & Venereol, Helsinki, Finland

[48] Helsinki Univ Hosp, Helsinki, Finland

[49] Royal Free Hosp, Dept Dermatol, London, England

[50] Fraunhofer Inst Translat Med & Pharmacol ITMP, Allergol, Berlin, Germany

来源：

ALLERGY | 2022年 / 77卷 / 03期

关键词：

angioedema; consensus; evidence-based; hives; itch; mast cell; urticaria; wheal; DELAYED PRESSURE URTICARIA; QUALITY-OF-LIFE; CHRONIC IDIOPATHIC URTICARIA; CHRONIC IDIOPATHIC/SPONTANEOUS URTICARIA; DOSE INTRAVENOUS IMMUNOGLOBULIN; RESISTANT CHRONIC URTICARIA; ULTRAVIOLET-B PHOTOTHERAPY; DOUBLE-BLIND; DISEASE-ACTIVITY; NONSEDATING ANTIHISTAMINES;

D O I：

10.1111/all.15090

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

This update and revision of the international guideline for urticaria was developed following the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is a joint initiative of the Dermatology Section of the European Academy of Allergology and Clinical Immunology (EAACI), the Global Allergy and Asthma European Network (GA(2)LEN) and its Urticaria and Angioedema Centers of Reference and Excellence (UCAREs and ACAREs), the European Dermatology Forum (EDF; EuroGuiDerm), and the Asia Pacific Association of Allergy, Asthma and Clinical Immunology with the participation of 64 delegates of 50 national and international societies and from 31 countries. The consensus conference was held on 3 December 2020. This guideline was acknowledged and accepted by the European Union of Medical Specialists (UEMS). Urticaria is a frequent, mast cell-driven disease that presents with wheals, angioedema, or both. The lifetime prevalence for acute urticaria is approximately 20%. Chronic spontaneous or inducible urticaria is disabling, impairs quality of life, and affects performance at work and school. This updated version of the international guideline for urticaria covers the definition and classification of urticaria and outlines expert-guided and evidence-based diagnostic and therapeutic approaches for the different subtypes of urticaria.

引用

页码：734 / 766

页数：33

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