RuCl3 catalyzed one-pot synthesis of α-aminonitriles

被引：79
作者：
De, SK
机构：
[1] Dept. Med. Chem./Molec. Pharmacol., Purdue Cancer Center, Purdue University, West Lafayette
来源：
SYNTHETIC COMMUNICATIONS | 2005年 / 35卷 / 05期
关键词：
aldehydes; amines; trimethylsilyl cyanide; alpha-aminonitriles; ruthenium trichloride;
D O I：
10.1081/SCC-200050347
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A simple and efficient method was developed for the synthesis of alpha-aminonitriles by simply mixing aldehydes, amines, and trimethylsilyl cyanides in the presence of a catalytic amount of RuCl3 at room temperature.
引用
收藏
页码：653 / 656
页数：4
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