Relationship between Neurocardiogenic Syncope and Ventricular Repolarization

被引：11

作者：

Sucu, Murat ^{[1
]}

Ozer, Orhan ^{[1
]}

Davutoglu, Vedat ^{[1
]}

Ercan, Suleyman ^{[1
]}

Yuce, Murat ^{[1
]}

Coskun, Fatma Yilmaz ^{[1
]}

机构：

[1] Gaziantep Univ, Dept Cardiol, Electrophysiol Div, Gaziantep, Turkey

来源：

PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY | 2015年 / 38卷 / 05期

关键词：

electrocardiogram; repolarization; neurocardiogenic syncope; TP-E/QT RATIO; TRANSMURAL DISPERSION; QT; INTERVAL; RISK; INDEX; PEAK;

D O I：

10.1111/pace.12599

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

BackgroundWe aimed to analyze ventricular repolarization in neurocardiogenic syncope (NCS) patients by using T-peak-T-end interval, T-peak-T-end/QT ratio, T-peak-T-end/QTc ratio and corrected QT interval (QTc), QT dispersion (QTd), QT index (QTI) and corrected QT interval index (QTcI) comparing with the corrected JT dispersion (JTcd), and corrected JT (JTc) and the corrected JT interval index (JTcI), by inspecting ventricular activation until termination of repolarization. These parameters are used as an index of potential ventricular arrhythmogenesis. MethodsWe have studied patients with head-up tilt table test (HUTT) (+) (33 patients; mean age: 28 11 years) and HUTT (-) as control group (33 patients; mean age: 30 11 years). In all patients, T-peak-T-end interval, T-peak-T-end/QT ratio, T-peak-T-end/QTc ratio, QT, QTd, QTI, QTc, QTcI, JTd, JTc, and JTcI were measured on electrocardiogram. ResultsThe following parameters were statistically significant between groups: QTd (22.72 +/- 17.54 msn; 11.21 +/- 13.40 msn; P = 0.004), QTc (424.27 +/- 33.75 msn; 403.66 +/- 38.08 msn; P = 0.023), QTcI (114.09 +/- 14, 29%; 106.71 +/- 15.33%, P = 0.047), and QTI (100.72 +/- 7.19%; 97.14 +/- 7.13%, P = 0.046). Furthermore, T-peak-T-end interval was significantly prolonged in the study group (93.78 +/- 20.27 msn; 81.21 +/- 11.66 msn; P = 0.003). T-peak-T-end/QT ratio was significantly higher in the study group (0.24 +/- 0.04 msn; 0.22 +/- 0.04 msn; P = 0.030). T-peak-T-end/QTc ratio was significantly higher in the study group (0.22 +/- 0.04 msn; 0.20 +/- 0.03 msn; P = 0.015). The JTc and JTd were also significantly higher in the study group ([103.00 +/- 9, 72%; 95.44 +/- 10.26%, P = 0.003], [27.57 +/- 16.01 msn; 10.45 +/- 16.08 msn; P < 0.001], respectively). ConclusionsElectrocardiographic ventricular repolarization parameters including T-peak-T-end interval, T-peak-T-end/QT ratio, T-peak-T-end/QTc ratio, QTc, QTd, QTI, QTcI, JTc, JTd, and JTI are prolonged in NCS.

引用

页码：625 / 629

页数：5

共 21 条

[11] Tp-e/QT ratio as an index of arrhythmogenesis [J].

Gupta, Prasad ;

Patel, Chinmay ;

Patel, Harsh ;

Narayanaswamy, Srinivasa ;

Malhotra, Binu ;

Green, Jared T. ;

Yan, Gan-Xin .

JOURNAL OF ELECTROCARDIOLOGY, 2008, 41 (06) :567-574

[12] The prognostic value of the Tpeak-Tend interval in patients undergoing primary percutaneous coronary intervention for ST-segment elevation myocardial infarction [J].

Haarmark, Christian ;

Hansen, Peter R. ;

Vedel-Larsen, Esben ;

Pedersen, Sune Haahr ;

Graff, Claus ;

Andersen, Mads P. ;

Toft, Egon ;

Wang, Fan ;

Struijk, Johannes J. ;

Kanters, Jorgen K. .

JOURNAL OF ELECTROCARDIOLOGY, 2009, 42 (06) :555-560

[13] Tp-e Interval, Tp-e/QT Ratio, and Tp-e/QTc Ratio are Prolonged in Patients with Moderate and Severe Obstructive Sleep Apnea [J].

Kilicaslan, Fethi ;

Tokatli, Alptug ;

Ozdag, Fatih ;

Uzun, Mehmet ;

Uz, Omer ;

Isilak, Zafer ;

Yiginer, Omer ;

Yalcin, Murat ;

Guney, Mehmet Senol ;

Cebeci, Bekir Sitki .

PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 2012, 35 (08) :966-972

[14] Circadian variation of QTc dispersion in children with vasovagal syncope [J].

Kula, S ;

Olgunturk, R ;

Tunaoglu, FS ;

Canter, B .

INTERNATIONAL JOURNAL OF CARDIOLOGY, 2004, 97 (03) :407-410

[15] New insight into repolarization abnormalities in patients with congenital long QT syndrome: The increased transmural dispersion of repolarization [J].

Lubinski, A ;

Lewicka-Nowak, E ;

Kempa, M ;

Baczynska, AM ;

Romanowska, I ;

Swiatecka, G .

PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY, 1998, 21 (01) :172-175

[16] Assessment of prolonged QT and JT intervals in ventricular conduction defects [J].

Rautaharju, PM ;

Zhang, ZM ;

Prineas, R ;

Heiss, G .

AMERICAN JOURNAL OF CARDIOLOGY, 2004, 93 (08) :1017-1021

[17] T-peak to T-end interval may be a better predictor of high-risk patients with hypertrophic cardiomyopathy associated with a cardiac troponin I mutation than QT dispersion [J].

Shimizu, M ;

Ino, H ;

Okeie, K ;

Yamaguchi, M ;

Nagata, M ;

Hayashi, K ;

Itoh, H ;

Iwaki, T ;

Oe, K ;

Konno, T ;

Mabuchi, H .

CLINICAL CARDIOLOGY, 2002, 25 (07) :335-339

[18] Transmural dispersion of repolarization and ventricular tachyarrhythmias [J].

Watanabe, N ;

Kobayashi, Y ;

Tanno, K ;

Miyoshi, F ;

Asano, T ;

Kawamura, M ;

Mikami, Y ;

Adachi, T ;

Ryu, S ;

Miyata, A ;

Katagiri, T .

JOURNAL OF ELECTROCARDIOLOGY, 2004, 37 (03) :191-200

[19] RR interval variation, the QT interval index and risk of primary cardiac arrest among patients without clinically recognized heart disease [J].

Whitsel, EA ;

Raghunathan, TE ;

Pearce, RM ;

Lin, D ;

Rautaharju, PM ;

Lemaitre, R ;

Siscovick, DS .

EUROPEAN HEART JOURNAL, 2001, 22 (02) :165-173

[20] Cellular basis for the normal T wave and the electrocardiographic manifestations of the long-QT syndrome [J].

Yan, GX ;

Antzelevitch, C .

CIRCULATION, 1998, 98 (18) :1928-1936

← 1 2 3 →