An update on the relationships between rheumatoid arthritis and atherosclerosis

被引：44
作者：
Ozbalkan, Zeynep [1 ]
Efe, Cumali [2 ]
Cesur, Mustafa [3 ]
Ertek, Sibel [4 ]
Nasiroglu, Narin [2 ]
Berneis, Kaspar [5 ,6 ]
Rizzo, Manfredi [7 ]
机构：
[1] Ankara Numune Hosp, Dept Rheumatol, Ankara, Turkey
[2] Ankara Numune Hosp, Dept Internal Med, Ankara, Turkey
[3] Ankara Guven Hosp, Dept Endocrinol, Ankara, Turkey
[4] Ufuk Univ Hosp, Dept Endocrinol, Ankara, Turkey
[5] Univ Zurich Hosp, Div Endocrinol Diabet & Clin Nutr, Zurich, Switzerland
[6] Univ Zurich, Zurich Ctr Integrat Human Physiol, CH-8006 Zurich, Switzerland
[7] Univ Palermo, Dept Clin Med & Emerging Dis, I-90133 Palermo, Italy
来源：
ATHEROSCLEROSIS | 2010年 / 212卷 / 02期
关键词：
Atherosclerosis; Rheumatoid arthritis; Inflammation; Cardiovascular risk; NECROSIS-FACTOR-ALPHA; CARDIOVASCULAR RISK-FACTORS; ENDOTHELIAL PROGENITOR CELLS; INTIMA-MEDIA THICKNESS; C-REACTIVE PROTEIN; INSULIN-RESISTANCE; DISEASE-ACTIVITY; INFLAMMATORY POLYARTHRITIS; AORTIC STIFFNESS; MORTALITY;
D O I：
10.1016/j.atherosclerosis.2010.03.035
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Rheumatoid arthritis is a chronic inflammatory disease. Cardiovascular events are the most important cause of mortality and morbidity in patients with rheumatoid arthritis. Beyond the traditional cardiovascular risk factors, chronic systemic inflammation has been shown to be a crucial factor in atherosclerosis development and progression from endothelial dysfunction to plaque rupture and thrombosis. Many studies have shown that atherosclerosis is not a passive event like accumulation of lipids in the vessel walls; by contrast, it represents an active inflammation of the vessels. Inflammatory cells such as macrophages, monocytes and T cells play important roles in the development of both rheumatoid arthritis and atherosclerosis. In this article we analyse the relationships between rheumatoid arthritis and atherosclerosis. (C) 2010 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：377 / 382
页数：6
相关论文
共 78 条
[1]   How to RECOVER from RENAISSANCE? The significance of the results of RECOVER, RENAISSANCE, RENEWAL and ATTACH [J].
Anker, SD ;
Coats, AJS .
INTERNATIONAL JOURNAL OF CARDIOLOGY, 2002, 86 (2-3) :123-130
[2]   Anti-rheumatic drug use and risk of hospitalization for congestive heart failure in rheumatoid arthritis [J].
Bernatsky, S ;
Hudson, M ;
Suissa, S .
RHEUMATOLOGY, 2005, 44 (05) :677-680
[3]   Impact of parental history on patients' cardiovascular mortality in rheumatoid arthritis [J].
Björnådal, L ;
Brandt, L ;
Klareskog, L ;
Askling, J .
ANNALS OF THE RHEUMATIC DISEASES, 2006, 65 (06) :741-745
[4]   Modulation of CD28 expression with anti-tumor necrosis factor α therapy in rheumatoid arthritis [J].
Bryl, E ;
Vallejo, AN ;
Matteson, EL ;
Witkowski, JM ;
Weyand, CM ;
Goronzy, JJ .
ARTHRITIS AND RHEUMATISM, 2005, 52 (10) :2996-3003
[5]  
CARNETHON MR, 2005, JAMA-J AM MED ASSOC, V21, P2981
[6]  
Charles-Schoeman C, 2007, J RHEUMATOL, V34, P1459
[7]   Abnormal vitamin B6 status is associated with severity of symptoms in patients with rheumatoid arthritis [J].
Chiang, EPI ;
Bagley, PJ ;
Selhub, J ;
Nadeau, M ;
Roubenoff, R .
AMERICAN JOURNAL OF MEDICINE, 2003, 114 (04) :283-287
[8]   Methotrexate and mortality in patients with rheumatoid arthritis:: a prospective study [J].
Choi, HK ;
Hernán, MA ;
Seeger, JD ;
Robins, JM ;
Wolfe, F .
LANCET, 2002, 359 (9313) :1173-1177
[9]   Response to anti-tumour necrosis factor alpha blockade is associated with reduction of carotid intima-media thickness in patients with active rheumatoid arthritis [J].
Del Porto, F. ;
Lagana, B. ;
Lai, S. ;
Nofroni, I. ;
Tinti, F. ;
Vitale, M. ;
Podesta, E. ;
Mitterhofer, A. P. ;
D'Amelio, R. .
RHEUMATOLOGY, 2007, 46 (07) :1111-1115
[10]  
del Rincón I, 2001, ARTHRITIS RHEUM-US, V44, P2737, DOI 10.1002/1529-0131(200112)44:12<2737::AID-ART460>3.0.CO
12345678