Clinical management of uterine papillary serous carcinoma

被引：15
作者：
Roelofsen, Thijs [1 ]
van Ham, Maaike A. [1 ]
de Hullu, Joanne A. [1 ]
Massuger, Leon F. [1 ]
机构：
[1] Radboud Univ Nijmegen, Med Ctr, Dept Obstet & Gynecol 791, NL-6500 HB Nijmegen, Netherlands
来源：
EXPERT REVIEW OF ANTICANCER THERAPY | 2011年 / 11卷 / 01期
关键词：
comprehensive surgical staging; cytoreductive surgery; endometrial cancer; papillary serous carcinoma; radiation therapy; uterine chemotherapy; PLATINUM-BASED CHEMOTHERAPY; CLEAR-CELL CARCINOMA; WHOLE ABDOMINOPELVIC RADIATION; EPITHELIAL OVARIAN-CARCINOMA; GYNECOLOGIC-ONCOLOGY-GROUP; LONG-TERM SURVIVAL; STAGE-I PATIENTS; ENDOMETRIAL CANCER; NEOADJUVANT CHEMOTHERAPY; ADJUVANT THERAPY;
D O I：
10.1586/ERA.10.199
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Uterine papillary serous carcinoma (UPSC) is an aggressive variant of endometrial cancer. Owing to its rarity, most clinicians are unfamiliar with the clinical aspects and management of UPSC. Furthermore, little prospective evidence exists regarding how best to treat this subset of patients. In anticipation of prospective clinical trials, this article summarizes the latest results of various clinical management options in the different substages of UPSC, with a special focus on the effects of cytoreductive surgery, comprehensive surgical staging and different adjuvant treatment options in relation to recurrence rate and survival outcome.
引用
收藏
页码：71 / 81
页数：11
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