ASSOCIATION OF RS172378 VARIANT IN C1Q GENE CLUSTER WITH SOME CLINICAL AND IMMUNOLOGICAL ASPECTS OF SYSTEMIC LUPUS ERYTHEMATOSUS IN BULGARIAN PATIENTS

被引：0
作者：
Kosturkova, M. [1 ]
Shivacheva, T. [2 ]
Mihaylova, G. [3 ]
Vasilev, V. [4 ]
Radanova, M. [3 ]
机构：
[1] Varna Med Univ, Dept Propedeut Internal Dis, Varna, Bulgaria
[2] Varna Med Univ, Dept Internal Dis 1, Varna, Bulgaria
[3] Varna Med Univ, Dept Biochem Mol Med & Nutrigen, Varna, Bulgaria
[4] Sofia Med Univ, Dept Nephrol, Sofia, Bulgaria
来源：
ANNALS OF THE RHEUMATIC DISEASES | 2022年 / 81卷
关键词：
POLYMORPHISM;
D O I：
10.1136/annrheumdis-2022-eular.2540
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
AB0007
引用
收藏
页码：1139 / 1139
页数：1
相关论文
共 8 条
[1]   Investigation of C1-complex regions reveals new C1Q variants associated with protection from systemic lupus erythematosus, and affect its transcript abundance [J].
Guo, Jianping ;
Gao, Yanyan ;
Wang, Yuxuan ;
Zou, Yundong ;
Du, Yan ;
Luo, Cainan ;
Shi, Yamei ;
Yang, Yue ;
Wu, Xinyu ;
Su, Yin ;
Wu, Lijun ;
Chen, Shi ;
Li, Zhanguo .
SCIENTIFIC REPORTS, 2018, 8
[2]   Analysis of C1q polymorphisms suggests association with systemic lupus erythematosus, serum C1q and CH50 levels and disease severity [J].
Martens, H. A. ;
Zuurman, M. W. ;
de Lange, A. H. M. ;
Nolte, I. M. ;
van der Steege, G. ;
Navis, G. J. ;
Kallenberg, C. G. M. ;
Seelen, M. A. ;
Bijl, M. .
ANNALS OF THE RHEUMATIC DISEASES, 2009, 68 (05) :715-720
[3]   C1q rs292001 polymorphism and C1q antibodies in juvenile lupus and their relation to lupus nephritis [J].
Mosaad, Y. M. ;
Hammad, A. ;
Fawzy, Z. ;
El-Refaaey, A. ;
Tawhid, Z. ;
Hammad, E. M. ;
Youssef, L. F. ;
ElAttar, E. A. A. ;
Radwan, D. F. ;
Fawzy, I. M. .
CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2015, 182 (01) :23-34
[4]   Identification of novel coding mutation in C1qA gene in an African-American pedigree with lupus and C1q deficiency [J].
Namjou, B. ;
Keddache, M. ;
Fletcher, D. ;
Dillon, S. ;
Kottyan, L. ;
Wiley, G. ;
Gaffney, P. M. ;
Wakeland, B. E. ;
Liang, C. ;
Wakeland, E. K. ;
Scofield, R. H. ;
Kaufman, K. ;
Harley, J. B. .
LUPUS, 2012, 21 (10) :1113-1118
[5]   Common silent mutations in all types of hereditary complement C1q deficiencies [J].
Petry, F ;
Loos, M .
IMMUNOGENETICS, 2005, 57 (08) :566-571
[6]   Homozygous single nucleotide polymorphism of the complement C1QA gene is associated with decreased levels of Clq in patients with subacute cutaneous lupus erythematosus [J].
Racila, DM ;
Sontheimer, CJ ;
Sheffield, A ;
Wisnieski, JJ ;
Racila, E ;
Sontheimer, RD .
LUPUS, 2003, 12 (02) :124-132
[7]   Association of rs172378 C1q gene cluster polymorphism with lupus nephritis in Bulgarian patients [J].
Radanova, M. ;
Vasilev, V. ;
Dimitrov, T. ;
Deliyska, B. ;
Ikonomov, V. ;
Ivanova, D. .
LUPUS, 2015, 24 (03) :280-289
[8]   Assessing association of common variation in the C1Q gene cluster with systemic lupus erythematosus [J].
Rafiq, S. ;
Frayling, T. M. ;
Vyse, T. J. ;
Graham, D. S. Cunninghame ;
Eggleton, P. .
CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2010, 161 (02) :284-289
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