Under-5-Years Child Mortality Due to Congenital Anomalies A Retrospective Study in Urban and Rural China in 1996-2013

被引:19
作者
Cui, Hao [1 ,2 ]
He, Chunhua [1 ]
Kang, Leni [1 ]
Li, Qi [1 ]
Miao, Lei [1 ]
Shen, Liqin [2 ]
Zhu, Jun [3 ]
Li, Xiaohong [1 ]
Wang, Yanping [3 ,4 ]
机构
[1] Sichuan Univ, West China Univ Hosp 2, Natl Ctr Birth Defects Monitoring China, Chengdu 610064, Sichuan, Peoples R China
[2] Sichuan Univ, West China Sch Publ Hlth, Chengdu 610064, Sichuan, Peoples R China
[3] Sichuan Univ, West China Univ Hosp 2, Natl Off Maternal & Child Hlth Surveillance China, Chengdu 610064, Sichuan, Peoples R China
[4] Sichuan Univ, Minist Educ, Key Lab Birth Defects & Related Dis Women & Child, Chengdu 610064, Sichuan, Peoples R China
关键词
INFANT-MORTALITY; SYSTEMATIC ANALYSIS; NEONATAL-MORTALITY; PRENATAL-DIAGNOSIS; BIRTH-DEFECTS; DOWN-SYNDROME; TRENDS; SURVIVAL; MALFORMATIONS; PREVALENCE;
D O I
10.1016/j.amepre.2015.12.013
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Introduction: Congenital anomalies (CAs) contribute significantly to under-5-years child mortality (U5M) throughout the world. This study analyzed trends in the CA-specific U5M rate in urban and rural China. Methods: This population-based epidemiologic study used data obtained by China's National U5M Surveillance System from 1996 to 2013. Data from national surveillance sites were used to examine CA-specific U5M rates by year, urban and rural habitation, and sex. Mixed effect negative binomial regression models were used to assess the trends in CA-specific U5M rates and differences in those trends between urban and rural areas. Results: The CA-specific U5M rate decreased from 407.7 per 100,000 live births in 1996 to 217.4 per 100,000 live births in 2013, with average annual decline rates of 6.4% (95% CI=5.6%, 7.1%) and 3.8% (95% CI=-3.3%, 4.3%) in urban and rural areas, respectively. The CA-specific U5M rate was the same in both rural and urban areas in 1996, but the U5M rate of the rural areas was 1.621-fold of that of urban areas in 2013. In urban and rural China, cardiovascular anomalies were the most frequent CAs, accounting for 50.3% and 58.2% of U5M due to CA, respectively. Conclusions: CAs have become one of the leading causes of U5M in both urban and rural China and the difference between the CA-specific U5M rates in two areas is gradually increasing. Reduction of child mortality due to CAs and elimination of the geographic disparity in child mortality rates should be major public health concerns in China. (C) 2016 American Journal of Preventive Medicine
引用
收藏
页码:663 / 671
页数:9
相关论文
共 46 条
  • [1] Agresti A., 1990, CATEGORICAL DATA ANA
  • [2] [Anonymous], 2012, CHIN REP BIRTH DEF 2
  • [3] [Anonymous], 2009, MILL DEV GOALS REP 2
  • [4] Folic acid to reduce neonatal mortality from neural tube disorders
    Blencowe, Hannah
    Cousens, Simon
    Modell, Bernadette
    Lawn, Joy
    [J]. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2010, 39 : 110 - 121
  • [5] Bryce J, 2008, LANCET, V371, P1247, DOI 10.1016/S0140-6736(08)60559-0
  • [6] World Health Organization perspectives on the contribution of the Global Alliance for Vaccines and Immunization on reducing child mortality
    Bustreo, F.
    Okwo-Bele, J-M
    Kamara, L.
    [J]. ARCHIVES OF DISEASE IN CHILDHOOD, 2015, 100 : S34 - S37
  • [7] Persistence of perinatal mortality due to congenital malformations in resource-poor settings
    Chhabra, S.
    Darwade, R.
    Dhawde, K.
    [J]. JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 2012, 32 (04) : 350 - 352
  • [8] Christianson A, 2006, GLOBAL REPORT BIRTH
  • [9] Using birth defects registry data to evaluate infant and childhood mortality associated with birth defects: An alternative to traditional mortality assessment using underlying cause of death statistics
    Copeland, Glenn E.
    Kirby, Russell S.
    [J]. BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY, 2007, 79 (11) : 792 - 797
  • [10] Recent trends in the birth prevalence of Down syndrome in China: impact of prenatal diagnosis and subsequent terminations
    Deng, Changfei
    Yi, Ling
    Mu, Yi
    Zhu, Jun
    Qin, Yanwen
    Fan, Xiaoxiao
    Wang, Yanping
    Li, Qi
    Dai, Li
    [J]. PRENATAL DIAGNOSIS, 2015, 35 (04) : 311 - 318