Enantioselective synthesis of cyclic sulfamidates via Pd-catalyzed hydrogenation

被引：139

作者：

Wang, You-Qing ^{[1
]}

Yu, Chang-Bin ^{[1
]}

Wang, Da-Wei ^{[1
]}

Wang, Xiao-Bing ^{[1
]}

Zhou, Yong-Gui ^{[1
]}

机构：

[1] Chinese Acad Sci, Dalian Inst Chem Phys, State Key Lab Catalysis, Dalian 116023, Peoples R China

来源：

ORGANIC LETTERS | 2008年 / 10卷 / 10期

关键词：

D O I：

10.1021/ol800591u

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Using Pd(CF3CO2)(2)/(SS)-f-binaphane as the catalyst, an efficient enantioselective synthesis of cyclic sulfamidates was developed via asymmetric hydrogenation of the corresponding cyclic imines in 2,2,2-trifluoroethanol at room temperature with high enantioselectivities (up to 99% ee).

引用

页码：2071 / 2074

页数：4

共 87 条

[81] A highly enantioselective, Pd-TangPhos-catalyzed hydrogenation of N-tosylimines [J].