TBAI-catalyzed oxidative coupling of aminopyridines with β-keto esters and 1,3-diones-synthesis of imidazo[1,2-a]pyridines

被引：242
|
作者：
Ma, Lijuan [1 ]
Wang, Xianpei [1 ]
Yu, Wei [1 ]
Han, Bing [1 ]
机构：
[1] Lanzhou Univ, Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 40期
基金：
中国国家自然科学基金;
关键词：
AMMONIUM (HYPO)IODITE CATALYSIS; SELECTIVE LIGANDS; BINDING-AFFINITY; BENZODIAZEPINE; POTENT; SERIES;
D O I：
10.1039/c1cc13568f
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
TBAI could catalyze the direct oxidative C-N coupling of 2-aminopyridines with beta-keto esters and 1,3-diones, which affords imidazo[1,2-a]pyridines as the products. The reaction was realized under metal-free conditions by using tert-butyl hydroperoxide (TBHP) as the oxidant.
引用
收藏
页码：11333 / 11335
页数：3
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