TBAI-catalyzed oxidative coupling of aminopyridines with β-keto esters and 1,3-diones-synthesis of imidazo[1,2-a]pyridines

被引：243

作者：

Ma, Lijuan ^{[1
]}

Wang, Xianpei ^{[1
]}

Yu, Wei ^{[1
]}

Han, Bing ^{[1
]}

机构：

[1] Lanzhou Univ, Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 40期

基金：

中国国家自然科学基金;

关键词：

AMMONIUM (HYPO)IODITE CATALYSIS; SELECTIVE LIGANDS; BINDING-AFFINITY; BENZODIAZEPINE; POTENT; SERIES;

D O I：

10.1039/c1cc13568f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

TBAI could catalyze the direct oxidative C-N coupling of 2-aminopyridines with beta-keto esters and 1,3-diones, which affords imidazo[1,2-a]pyridines as the products. The reaction was realized under metal-free conditions by using tert-butyl hydroperoxide (TBHP) as the oxidant.

引用

页码：11333 / 11335

页数：3

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