A fast image reconstruction algorithm based on penalized-likelihood estimate

Statistical iterative methods for image reconstruction like maximum likelihood expectation maximization (ML-EM) are more robust and flexible than analytical inversion methods and allow for accurately modeling the counting statistics and the photon transport during acquisition. They are rapidly becoming the standard for image reconstruction in emission computed tomography. The maximum likelihood approach provides images with superior noise characteristics compared to the conventional filtered back projection algorithm. But a major drawback of the statistical iterative image reconstruction is its high computational cost. In this paper, a fast algorithm is proposed as a modified OS-EM (MOS-EM) using a penalized function, which is applied to the least squares merit function to accelerate image reconstruction and to achieve better convergence. The experimental results show that the algorithm can provide high quality reconstructed images with a small number of iterations. (c) 2005 IPEM. Published by Elsevier Ltd. All rights reserved.