Synthesis of aromatic aldehyde acetals from (dibromomethyl)arenes

被引：7
作者：
Gazizov, M. B. [1 ]
Ivanova, S. Yu. [1 ]
Bashkirtseva, N. Yu. [1 ]
Khairullina, O. D. [1 ]
Khairullin, R. A. [1 ]
Gazizova, O. V. [1 ]
机构：
[1] Kazan Natl Res Technol Univ, 68 Ul Karl Marx, Kazan 420015, Russia
来源：
RUSSIAN CHEMICAL BULLETIN | 2017年 / 66卷 / 07期
关键词：
acetals; trialkyl orthoformates; (dibromomethyl)arenes; debromoalkoxylation; zinc chloride; alpha-brominated ethers; 4-(DIBROMOMETHYL)BENZENECARBALDEHYDE;
D O I：
10.1007/s11172-017-1877-6
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Zinc chloride-catalyzed double debromoalkoxylation of (dibromomethyl)arenes on treatment with trialkyl orthoformates resulted in the corresponding aromatic aldehyde acetals. On the first step, alpha-brominated ether is formed, which undergoes the second debromoalkoxylation producing acetal. This method is tolerated to ester functionalized derivatives.
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收藏
页码：1230 / 1233
页数：4
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