Inducible Alveolar Epithelial Type II (AT2) Cell -Specific Grp78 Knockout Mice Develop Endoplasmic Reticulum (ER) Stress and Reversible Pulmonary Fibrosis

被引：0
|
作者：
Zhou, B. [1 ]
Wang, H. [1 ]
Liu, Y. [1 ]
Flodby, P. [1 ]
Crandall, E. D. [1 ]
Lee, A. [2 ,3 ]
Borok, Z. [1 ]
机构：
[1] Univ Southern Calif, Div Pulm Crit Care & Sleep Med, Dept Med, Los Angeles, CA USA
[2] Univ Southern Calif, USC Norris Comprehens Canc Ctr, Los Angeles, CA USA
[3] Univ Southern Calif, Dept Biochem & Mol Biol, Los Angeles, CA USA
来源：
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE | 2018年 / 197卷
关键词：
D O I：
暂无
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
A6206
引用
收藏
页数：2
相关论文
共 34 条
  • [1] Effects of Endoplasmic Reticulum (ER) Stress on Epithelial Injury and Fibrosis in Alveolar Epithelial Type II Cell (AT2)-Specific Grp78 Knockout Mice
    Zhou, Beiyun
    Flodby, Per
    Wang, Hongjun
    Liu, Yixin
    Minoo, Parviz
    Crandall, Edward
    Lee, Amy
    Borok, Zea
    FASEB JOURNAL, 2015, 29
  • [2] Endoplasmic Reticulum (er) Stress Exacerbates Pulmonary Fibrosis In Inducible Alveolar Epithelial Type Ii Cell-Specific Grp78 Knockout Mice
    Flodby, P.
    Li, C.
    Wang, H.
    Liu, Y.
    Rieger, M.
    Kahn, M.
    Beers, M. F.
    Lee, A. S.
    Minoo, P.
    Crandall, E. D.
    Borok, Z.
    Zhou, B.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2016, 193
  • [3] ER Stress-Induced Mitochondrial Dysfunction Contributes to Alveolar Epithelial Cell Injury in AT2 Cell-Specific Grp78 Knockout Mice
    Zhou, B.
    Qi, Y.
    Liu, Y.
    Minoo, P.
    Li, C.
    Lee, A.
    Ann, D.
    Borok, Z.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2021, 203 (09)
  • [4] Transcriptomic Analysis Identifies Pathways Mediating Alveolar Epithelial Type II (AT2) Cell Dysfunction and Fibrosis in Response to ER Stress Following Grp78 Knockout (KO)
    Zhou, B.
    Horie, M.
    Flodby, P.
    Wang, H.
    Liu, Y.
    Lee, A.
    Borok, Z.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2019, 199
  • [5] C/EBP Homologous Protein (CHOP) Is a Key Regulator of Lung Fibrosis in Alveolar Epithelial Type II (AT2)-specific Grp78 Knockout (KO) Mice
    Chen, W.
    Liu, Y.
    Li, C.
    Liebler, J. M.
    Crandall, E. D.
    Kim, K.
    Minoo, P.
    Lee, A.
    Borok, Z.
    Ann, D.
    Zhou, B.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2023, 207
  • [6] Grp78 Loss in Epithelial Progenitors Reveals an Age-linked Role for Endoplasmic Reticulum Stress in Pulmonary Fibrosis
    Borok, Zea
    Horie, Masafumi
    Flodby, Per
    Wang, Hongjun
    Liu, Yixin
    Ganesh, Sivagini
    Firth, Amy L.
    Minoo, Parviz
    Li, Changgong
    Beers, Michael F.
    Lee, Amy S.
    Zhou, Beiyun
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2020, 201 (02) : 198 - 211
  • [7] Endoplasmic Reticulum (er) Stress And Protein Acetylation Increase Grp78 Secretion By Airway Epithelial Cells
    Aksoy, M.
    Ji, R.
    Barrero, C.
    Merali, S.
    Kelsen, S.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2013, 187
  • [8] Coupling endoplasmic reticulum stress to the cell death program: role of the ER chaperone GRP78
    Rao, RV
    Peel, A
    Logvinova, A
    del Rio, G
    Hermel, E
    Yokota, T
    Goldsmith, PC
    Ellerby, LM
    Ellerby, HM
    Bredesen, DE
    FEBS LETTERS, 2002, 514 (2-3) : 122 - 128
  • [9] The endoplasmic reticulum (ER) chaperone GRP78 is secreted during ER Stress and alleviates endothelial cell inflammation
    Repges, E.
    Al Zaidi, M.
    Jansen, F.
    Zimmer, S.
    Tiyerlili, V.
    Aksoy, A.
    EUROPEAN HEART JOURNAL, 2022, 43 : 2938 - 2938
  • [10] The endoplasmic reticulum (ER) chaperone GRP78 is secreted during ER Stress and alleviates endothelial cell inflammation
    Repges, E.
    Al Zaidi, M. A. Z.
    Jansen, F. J.
    Zimmer, S. Z.
    Tiyerlili, V. T.
    Nickenig, G. N.
    Aksoy, A. A.
    EUROPEAN HEART JOURNAL, 2023, 44
1234