Genetics, diagnostics and therapeutic advances in NAFLD

被引:55
作者
Rinella, Mary E. [1 ]
Sanyal, Arun J. [2 ]
机构
[1] Northwestern Univ, Feinberg Sch Med, Chicago, IL 60527 USA
[2] Virginia Commonwealth Univ, VCU Sch Med, Richmond, VA 23298 USA
关键词
FATTY LIVER-DISEASE; HEPATOCELLULAR-CARCINOMA; STEATOHEPATITIS; POPULATION;
D O I
10.1038/nrgastro.2014.232
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
In 2014, NAFLD was confirmed as the fastest growing aetiology for hepatocellular cancer in the USA. However, 2014 also saw progress in our understanding of the heritability and pathogenesis of NAFLD, and an important clinical trial targeting the farnesoid X receptor pathway has illustrated advances in developing a pharmacological therapy.
引用
收藏
页码:65 / 66
页数:2
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