DNA repair: The Nijmegen breakage syndrome protein

被引：48
作者：
Featherstone, C
Jackson, SP
机构：
[1] Univ Cambridge, Wellcome Canc Res Campaign Inst, Cambridge CB2 1QR, England
[2] Univ Cambridge, Dept Zool, Cambridge CB2 1QR, England
来源：
CURRENT BIOLOGY | 1998年 / 8卷 / 17期
关键词：
D O I：
10.1016/S0960-9822(98)70392-6
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The gene mutated in Nijmegen breakage syndrome, a chromosome instability disorder, has been identified and sequenced. The protein product of this gene forms a complex with hMre11 and hRad50 - proteins that are involved in repairing double-strand breaks in DNA.
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收藏
页码：R622 / R625
页数：4
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