Bevacizumab, irinotecan, and temozolomide with re-irradiation in adult recurrent medulloblastoma: A first case report

被引：1
|
作者：
Yamauchi, Takahiro [1 ,4 ]
Kitai, Ryuhei [1 ,2 ]
Arai, Hiroshi [3 ]
Kidoguchi, Masamune [3 ]
Isozaki, Makoto [1 ]
Kodera, Toshiaki [1 ]
Kikuta, Ken-ichiro [1 ]
机构：
[1] Univ Fukui, Div Med, Dept Neurosurg, Fac Med Sci, 23-3 Matsuokashimoaizuki,Eiheiji Cho, Fukui 9101193, Japan
[2] Kaga Med Ctr, Dept Neurosurg, Kaga, Ishikawa, Japan
[3] Municipal Tsuruga Hosp, Dept Neurosurg, Tsuruga, Fukui, Japan
[4] Univ Fukui, Dept Hematol & Oncol, Fac Med Sci, Fukui, Japan
来源：
INTERDISCIPLINARY NEUROSURGERY-ADVANCED TECHNIQUES AND CASE MANAGEMENT | 2021年 / 25卷
关键词：
Adult recurrent medulloblastoma; Bevacizumab; Irinotecan; Temozolomide; PROGNOSTIC-FACTORS; PHASE-II; CHILDREN; CHEMOTHERAPY; SURVIVAL; THERAPY; TUMOR;
D O I：
10.1016/j.inat.2021.101249
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Medulloblastoma in adults is very rare, and there is no effective therapy for its initial appearance or recurrence. We present a case of a 40-year-old male with recurrent medulloblastoma despite initial radiochemotherapy. He received re-irradiation and 6 courses of bevacizumab, irinotecan, and temozolomide after which he remained stable for 6 months. This regimen may be promising for recurrent medulloblastoma in adults.
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页数：4
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