Tyrosol and tryptophol produced by Ceratocystis adiposa

Extracellular tyrosol and tryptophol were produced and isolated from the phytopathogen fungus Ceratocystis adiposa cultivated in a rich broth. These compounds have not been previously reported in this Ceratocystis species, as its identification was established through spectroscopic methods (H-1 NMR, C-13 NMR and MS). Productivity of tyrosol and tryptophol was 65.3 and 44 mu g l(-1) day(-1), respectively, which were values higher than those reported to date. Tyrosol is a compound of pharmaceutical interest showing antioxidating activity, a property used in the treatment of atherosclerosis. Tryptophol is reported to have antibiotic and phytotoxic activity.