Adverse effects of subthalamic nucleus DBS in a patient with multiple system atrophy

被引：41
作者：
Tarsy, D [1 ]
Apetauerova, D [1 ]
Ryan, P [1 ]
Norregaard, T [1 ]
机构：
[1] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Dept Neurol,Div Neurosurg, Boston, MA 02215 USA
来源：
NEUROLOGY | 2003年 / 61卷 / 02期
关键词：
D O I：
10.1212/01.WNL.0000073986.74883.36
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
A 59-year-old woman with levodopa-responsive parkinsonism complicated by motor fluctuations and generalized levodopa dyskinesia underwent bilateral subthalamic deep brain stimulation (STN DBS) 7 years after symptom onset. DBS improved levodopa-responsive upper extremity bradykinesia but aggravated speech, swallowing, and gait. Motor fluctuations were not improved and levodopa dose remained unchanged. Pulse generators were turned off. Clinical features and brain MRI in this case were indicative of multiple system atrophy (MSA). STN DBS is not recommended for patients with MSA.
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页码：247 / 249
页数：3
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