Droplet digital polymerase chain reaction for DNMT3A and IDH1/2 mutations to improve early detection of acute myeloid leukemia relapse after allogeneic hematopoietic stem cell transplantation

被引:53
作者
Brambati, Chiara [1 ]
Galbiati, Silvia [2 ]
Xue, Elisabetta [1 ,3 ]
Toffalori, Cristina [1 ]
Crucitti, Lara [3 ]
Greco, Raffaella [3 ]
Sala, Elisa [3 ]
Crippa, Alessandra [4 ]
Chiesa, Lorenza [1 ]
Soriani, Nadia [2 ]
Mazzi, Benedetta [1 ]
Tresoldi, Cristina [4 ]
Stanghellini, Maria Teresa Lupo [3 ]
Peccatori, Jacopo [3 ]
Carrabba, Matteo G. [3 ]
Bernardi, Massimo [3 ]
Ferrari, Maurizio [2 ]
Lampasona, Vito [2 ]
Ciceri, Fabio [3 ]
Vago, Luca [1 ,3 ]
机构
[1] IRCCS San Raffaele Sci Inst, Unit Immunogenet Leukemia Genom & Immunobiol, Milan, Italy
[2] IRCCS San Raffaele Sci Inst, Genom Diag Human Pathol Unit, Milan, Italy
[3] IRCCS San Raffaele Sci Inst, Unit Hematol & Bone Marrow Transplantat, Milan, Italy
[4] IRCCS San Raffaele Sci Inst, Mol Hematol Lab, Milan, Italy
关键词
acute myeloid leukemia; cytogenetics and molecular genetics; minimal residual disease; stem cell transplantation; droplet digital PCR; TIME; EVOLUTION; AML; PCR;
D O I
10.3324/haematol.2015.135467
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页数:5
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