Characterization of N-phosphoryl oligopeptide libaries by ESI-MS and HPLC-MS

被引:0
|
作者
Cao, SX
Su, YQ
Zhang, JC
Liu, HX
Zhao, YF [1 ]
机构
[1] Zhengzhou Univ, Dept Chem, Key Lab Chem Biol, Henan, Peoples R China
[2] Tsing Hua Univ, Sch Life Sci & Engn, Dept Chem, Minist Educ,Key Lab Bioorgan Phosphorus Chem & Ch, Beijing 100084, Peoples R China
来源
LETTERS IN PEPTIDE SCIENCE | 2003年 / 10卷 / 5-6期
关键词
ESI-MS; homo-oligopeptide library; HPLC-MS; N-phosphoryl oligopeptide library;
D O I
10.1023/B:LIPS.0000049160.28924.4b
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
N-diisopropyloxyphosphoryl oligopeptide libraries were constructed through the transformation from the homo-oligopeptide libraries, which were synthesized with the assistance of phosphorus oxychloride. The molecular mass distributions of N-phosphoryl oligopeptide libraries were monitored by ESI-MS, and the components identification and quantitative analysis were carried out by HPLC-MS.
引用
收藏
页码:631 / 635
页数:5
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