Low-level Laser Therapy Associated With High Intensity Resistance Training on Cardiac Autonomic Control of Heart Rate and Skeletal Muscle Remodeling in Wistar Rats

被引：14

作者：

Paolillo, Fernanda Rossi ^{[1
]}

Ross, Arena ^{[2
,3
]}

Dutra, Daniela Bassi ^{[4
]}

Marqueti Durigan, Rita de Cassia ^{[5
]}

de Araujo, Heloisa Selistre ^{[6
]}

Dutra de Souza, Hugo Celso ^{[7
]}

Parizotto, Nivaldo Antonio ^{[8
]}

Cipriano, Gerson, Jr. ^{[5
]}

Chiappa, Gaspar ^{[9
,10
,11
]}

Borghi-Silva, Audrey ^{[4
]}

机构：

[1] Univ Sao Paulo, Opt Grp, Phys Inst Sao Carlos IFSC, BR-05508 Sao Paulo, Brazil

[2] Univ Illinois, Coll Appl Hlth Sci, Dept Phys Therapy, Chicago, IL USA

[3] Univ Illinois, Coll Appl Hlth Sci, Integrat Physiol Lab, Chicago, IL USA

[4] Fed Univ Sao Carlos UFSCar, Cardiopulm Physiotherapy Lab, Dept Phys Therapy, BR-13565905 Sao Carlos, SP, Brazil

[5] Univ Brasilia UNB, Fac Ceilandia, Brasilia, DF, Brazil

[6] Fed Univ Sao Carlos UFSCar, Dept Physiol Sci, BR-13565905 Sao Carlos, SP, Brazil

[7] Univ Sao Paulo, Ribeirao Preto Med Sch FMRP, BR-05508 Sao Paulo, Brazil

[8] Fed Univ Sao Carlos UFSCar, Electrothermophototherapy Lab, Dept Phys Therapy, BR-13565905 Sao Carlos, SP, Brazil

[9] Coll Serra Gaucha, Div Phys Therapy, Sao Pelegrino, Brazil

[10] Hosp Clin Porto Alegre, Exercise Pathophysiol Res Lab, Porto Alegre, RS, Brazil

[11] Hosp Clin Porto Alegre, Div Cardiol, Porto Alegre, RS, Brazil

来源：

LASERS IN SURGERY AND MEDICINE | 2014年 / 46卷 / 10期

基金：

巴西圣保罗研究基金会;

关键词：

resistance training; LLLT; lactate; MMP-2; HRV; RATE-VARIABILITY; MMP-2; ACTIVITY; EXERCISE; EXPRESSION; IRRADIATION; CELLS; STRENGTH; IMPROVES; FATIGUE; NM;

D O I：

10.1002/lsm.22298

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Background and ObjectivePhototherapy plus dynamic exercise can enhance physical performance and improve health. The aim of our study was to evaluate the effect of low-level laser therapy (LLLT) associated with high intensity resistance training (HIT) on cardiac autonomic and muscle metabolic responses in rats. Study Design/Materials and MethodsForty Wistar rats were randomized into 4 groups: sedentary control (CG), HIT, LLLT and HIT+LLLT. HIT was performed 3 times/week for 8 weeks with loads attached to the tail of the animal. The load was gradually increased by 10% of body mass until reaching a maximal overload. For LLLT, irradiation parameters applied to the tibialis anterior (TA) muscle were as follows: infrared laser (780nm), power of 15mW for 10 seconds, leading to an irradiance of 37.5mW/cm(2), energy of 0.15J per point and fluency of 3.8J/cm(2). Blood lactate (BL), matrix metalloproteinase gelatinase A (MMP-2) gene expression and heart rate variability (HRV) indices were performed. ResultsBL significantly increased after 8-weeks for HIT, LLLT and HIT+LLLT groups. However, peak lactate when normalized by maximal load was significantly reduced for both HIT and HIT+LLLT groups (P<0.05). MMP-2 in the active form was significantly increased after HIT, LLLT and HIT+LLLT compared tom the CG (P<0.05). There was a significant reduction in low frequency [LF (ms(2))] and increase in high frequency [HF (un)] and HF (ms(2))] for the HIT, LLLT and HIT+LLLT groups compared with the CG (P<0.05). However, the LF/HF ratio was further reduced in the LLLT and HIT+LLLT groups compared to the CG and HIT group (P<0.05). ConclusionThese results provide evidence for the positive benefits of LLLT and HIT with respect to enhanced muscle metabolic and cardiac autonomic function in Wistar rats. Lasers Surg. Med. 46:796-803, 2014. (c) 2014 Wiley Periodicals, Inc.

引用

页码：796 / 803

页数：8