Polymer-Based Materials and their Applications in Image-Guided Cancer Therapy

被引:2
作者
Sun, Yang [1 ]
Ran, Haitao [1 ]
Liu, Fan [1 ]
机构
[1] Chongqing Med Univ, Chongqing Key Lab Ultrasound Mol Imaging, Affiliated Hosp 2, Dept Ultrasound, Chongqing 400010, Peoples R China
基金
中国国家自然科学基金;
关键词
Polymer; nanocarrier; theranostics; molecular imaging; targeted therapy; cancer; INTENSITY FOCUSED ULTRASOUND; ACOUSTIC DROPLET VAPORIZATION; IRON-OXIDE NANOPARTICLES; SYNERGISTIC HIFU ABLATION; CONTRAST AGENT; DRUG-DELIVERY; MULTIFUNCTIONAL MICROBUBBLES; PERFLUOROCARBON DROPLETS; MAGNETIC NANOPARTICLES; BREAST-CANCER;
D O I
10.2174/0929867328666210616160717
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Background: Advances in nanotechnology have enabled the combination of disease diagnosis and therapy into a single nano package that has tremendous potential for the development of new theranostic strategies. The variety of polymer-based materials has grown exponentially over the past several decades. Such materials have great potential as carriers in disease detection imaging and image monitoring and in systems for the precise delivery of drugs to specific target sites. Objective: In the present article, we review recent key developments in the synthesis of polymer-based materials for various medical applications and their clinical trials. Conclusion: There is a growing range of multi-faceted, polymer-based materials with various functions. These functions include carriers for image contrast agents, drug delivery systems, and real-time image-guided systems for noninvasive or minimally invasive therapeutic procedures for cancer therapy.
引用
收藏
页码:1352 / 1368
页数:17
相关论文
共 120 条
[1]   PLGA nanoparticles containing various anticancer agents and tumour delivery by EPR effect [J].
Acharya, Sarbari ;
Sahoo, Sanjeeb K. .
ADVANCED DRUG DELIVERY REVIEWS, 2011, 63 (03) :170-183
[2]   In vitro MRI of biodegradable hybrid (iron oxide/polycaprolactone) magnetic nanoparticles prepared via modified double emulsion evaporation mechanism [J].
Ahmed, Naveed ;
Ahmad, Nasir M. ;
Fessi, Hatem ;
Elaissari, Abdelhamid .
COLLOIDS AND SURFACES B-BIOINTERFACES, 2015, 130 :264-271
[3]   Trapping Pd(0) in nanoparticle-assembled microcapsules: an efficient and reusable catalyst [J].
Amali, Arlin Jose ;
Rana, Rohit Kumar .
CHEMICAL COMMUNICATIONS, 2008, (35) :4165-4167
[4]   The History of Nanoscience and Nanotechnology: From Chemical-Physical Applications to Nanomedicine [J].
Bayda, Samer ;
Adeel, Muhammad ;
Tuccinardi, Tiziano ;
Cordani, Marco ;
Rizzolio, Flavio .
MOLECULES, 2020, 25 (01)
[5]   The mechanism of nanoparticle-mediated enhanced energy transfer during high-intensity focused ultrasound sonication [J].
Bera, Chandan ;
Devarakonda, Surendra B. ;
Kumar, Vishal ;
Ganguli, Ashok K. ;
Banerjee, Rupak K. .
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2017, 19 (29) :19075-19082
[6]   High-Intensity Focused Ultrasound for the Treatment of Prostate Cancer: A Review [J].
Chaussy, Christian G. ;
Thueroff, Stefan .
JOURNAL OF ENDOUROLOGY, 2017, 31 :S30-S37
[7]   Imaging with ultrasound contrast agents: current status and future [J].
Chong, Wui K. ;
Papadopoulou, Virginie ;
Dayton, Paul A. .
ABDOMINAL RADIOLOGY, 2018, 43 (04) :762-772
[8]   Gold nanorod-encapsulated biodegradable polymeric matrix for combined photothermal and chemo-cancer therapy [J].
Chuang, Chun-Chiao ;
Cheng, Chih-Chi ;
Chen, Pei-Ying ;
Lo, Chieh ;
Chen, Yi-Ning ;
Shih, Min-Hsiung ;
Chang, Chien-Wen .
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2019, 14 :181-193
[9]   MRI-Guided HIFU Methods for the Ablation of Liver and Renal Cancers [J].
de Senneville, Baudouin Denis ;
Moonen, Chrit ;
Ries, Mario .
THERAPEUTIC ULTRASOUND, 2016, 880 :43-63
[10]   A Laser-Activated Biocompatible Theranostic Nanoagent for Targeted Multimodal Imaging and Photothermal Therapy [J].
Deng, Liming ;
Cai, Xiaojun ;
Sheng, Danli ;
Yang, Yang ;
Strohm, Eric M. ;
Wang, Zhigang ;
Ran, Haitao ;
Wang, Dong ;
Zheng, Yuanyi ;
Li, Pan ;
Shang, Tingting ;
Ling, Yi ;
Wang, Fengjuan ;
Sun, Yang .
THERANOSTICS, 2017, 7 (18) :4410-4423