Aqueous hydrotrope: an efficient and reusable medium for a green one-pot, diversity-oriented synthesis of quinazolinone derivatives

被引：20

作者：

Patil, Amol ^{[1
]}

Barge, Madhuri ^{[1
]}

Rashinkar, Gajanan ^{[1
]}

Salunkhe, Rajashri ^{[1
]}

机构：

[1] Shivaji Univ, Dept Chem, Kolhapur 416004, MS, India

来源：

MOLECULAR DIVERSITY | 2015年 / 19卷 / 03期

关键词：

Hydrotrope; Quinazolinones; Diversity-oriented synthesis (DOS); Multicomponent reaction; Aqueous medium; 3-COMPONENT SYNTHESIS; CATALYST; 2,3-DIHYDROQUINAZOLIN-4(1H)-ONES; WATER; NANOPARTICLES; ACID;

D O I：

10.1007/s11030-015-9580-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A library of quinazolinones was prepared by the one-pot three-component reaction of isatoic anhydride, ammonium salts/amines, and various electrophiles using aqueous hydrotropic solution as an efficient, economical, reusable, and green medium giving good to excellent yields of products in very short time. The method offers a versatile way for the development of diversity-oriented synthesis of quinazolinones.

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收藏

页码：435 / 445

页数：11

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